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Amino acid metabolic origin as an evolutionary influence on protein sequence in yeast.
de Bivort BL, Perlstein EO, Kunes S, Schreiber SL. de Bivort BL, et al. Among authors: perlstein eo. J Mol Evol. 2009 May;68(5):490-7. doi: 10.1007/s00239-009-9218-5. Epub 2009 Apr 9. J Mol Evol. 2009. PMID: 19357800 Free PMC article.
Evolutionarily conserved optimization of amino acid biosynthesis.
Perlstein EO, de Bivort BL, Kunes S, Schreiber SL. Perlstein EO, et al. J Mol Evol. 2007 Aug;65(2):186-96. doi: 10.1007/s00239-007-0013-x. Epub 2007 Aug 7. J Mol Evol. 2007. PMID: 17684697
Quantifying fitness distributions and phenotypic relationships in recombinant yeast populations.
Perlstein EO, Deeds EJ, Ashenberg O, Shakhnovich EI, Schreiber SL. Perlstein EO, et al. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10553-8. doi: 10.1073/pnas.0704037104. Epub 2007 Jun 12. Proc Natl Acad Sci U S A. 2007. PMID: 17566105 Free PMC article.
Revealing complex traits with small molecules and naturally recombinant yeast strains.
Perlstein EO, Ruderfer DM, Ramachandran G, Haggarty SJ, Kruglyak L, Schreiber SL. Perlstein EO, et al. Chem Biol. 2006 Mar;13(3):319-27. doi: 10.1016/j.chembiol.2006.01.010. Chem Biol. 2006. PMID: 16638537
Global nucleosome occupancy in yeast.
Bernstein BE, Liu CL, Humphrey EL, Perlstein EO, Schreiber SL. Bernstein BE, et al. Among authors: perlstein eo. Genome Biol. 2004;5(9):R62. doi: 10.1186/gb-2004-5-9-r62. Epub 2004 Aug 20. Genome Biol. 2004. PMID: 15345046 Free PMC article.
Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway.
Butcher RA, Bhullar BS, Perlstein EO, Marsischky G, LaBaer J, Schreiber SL. Butcher RA, et al. Among authors: perlstein eo. Nat Chem Biol. 2006 Feb;2(2):103-9. doi: 10.1038/nchembio762. Epub 2006 Jan 15. Nat Chem Biol. 2006. PMID: 16415861
Using expression and genotype to predict drug response in yeast.
Ruderfer DM, Roberts DC, Schreiber SL, Perlstein EO, Kruglyak L. Ruderfer DM, et al. Among authors: perlstein eo. PLoS One. 2009 Sep 4;4(9):e6907. doi: 10.1371/journal.pone.0006907. PLoS One. 2009. PMID: 19730698 Free PMC article.
Harnessing gene expression to identify the genetic basis of drug resistance.
Chen BJ, Causton HC, Mancenido D, Goddard NL, Perlstein EO, Pe'er D. Chen BJ, et al. Among authors: perlstein eo. Mol Syst Biol. 2009;5:310. doi: 10.1038/msb.2009.69. Epub 2009 Oct 13. Mol Syst Biol. 2009. PMID: 19888205 Free PMC article.
The antidepressant sertraline targets intracellular vesiculogenic membranes in yeast.
Rainey MM, Korostyshevsky D, Lee S, Perlstein EO. Rainey MM, et al. Among authors: perlstein eo. Genetics. 2010 Aug;185(4):1221-33. doi: 10.1534/genetics.110.117846. Epub 2010 May 10. Genetics. 2010. PMID: 20457874 Free PMC article.
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