Perno CF - Search Results

1

Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.

Baba M, Tanaka H, De Clercq E, Pauwels R, Balzarini J, Schols D, Nakashima H, Perno CF, Walker RT, Miyasaka T. Baba M, et al. Among authors: perno cf. Biochem Biophys Res Commun. 1989 Dec 29;165(3):1375-81. doi: 10.1016/0006-291x(89)92756-3. Biochem Biophys Res Commun. 1989. PMID: 2575380

2

2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.

Balzarini J, Pérez-Pérez MJ, San-Félix A, Schols D, Perno CF, Vandamme AM, Camarasa MJ, De Clercq E. Balzarini J, et al. Among authors: perno cf. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4392-6. doi: 10.1073/pnas.89.10.4392. Proc Natl Acad Sci U S A. 1992. PMID: 1374900 Free PMC article.

3

Activity of acyclic nucleoside phosphonate analogues against human immunodeficiency virus in monocyte/macrophages and peripheral blood lymphocytes.

Balzarini J, Perno CF, Schols D, De Clercq E. Balzarini J, et al. Among authors: perno cf. Biochem Biophys Res Commun. 1991 Jul 15;178(1):329-35. doi: 10.1016/0006-291x(91)91818-w. Biochem Biophys Res Commun. 1991. PMID: 2069572

4

Activity of the (R)-enantiomers of 9-(2-phosphonylmethoxypropyl)-adenine and 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine against human immunodeficiency virus in different human cell systems.

Balzarini J, Aquaro S, Perno CF, Witvrouw M, Holý A, De Clercq E. Balzarini J, et al. Among authors: perno cf. Biochem Biophys Res Commun. 1996 Feb 15;219(2):337-41. doi: 10.1006/bbrc.1996.0234. Biochem Biophys Res Commun. 1996. PMID: 8604988

5

Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication.

Balzarini J, Pelemans H, Aquaro S, Perno CF, Witvrouw M, Schols D, De Clercq E, Karlsson A. Balzarini J, et al. Among authors: perno cf. Mol Pharmacol. 1996 Aug;50(2):394-401. Mol Pharmacol. 1996. PMID: 8700148

6

Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).

Balzarini J, Naesens L, Aquaro S, Knispel T, Perno C, De Clercq E, Meier C. Balzarini J, et al. Mol Pharmacol. 1999 Dec;56(6):1354-61. doi: 10.1124/mol.56.6.1354. Mol Pharmacol. 1999. PMID: 10570065

7

Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.

Perno CF, Yarchoan R, Balzarini J, Bergamini A, Milanese G, Pauwels R, De Clercq E, Rocchi G, Calio R. Perno CF, et al. Antiviral Res. 1992 Apr;17(4):289-304. doi: 10.1016/0166-3542(92)90024-y. Antiviral Res. 1992. PMID: 1322645

8

Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.

Balzarini J, Karlsson A, Aquaro S, Perno CF, Cahard D, Naesens L, De Clercq E, McGuigan C. Balzarini J, et al. Among authors: perno cf. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7295-9. doi: 10.1073/pnas.93.14.7295. Proc Natl Acad Sci U S A. 1996. PMID: 8692986 Free PMC article.

9

Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

Balzarini J, Kruining J, Wedgwood O, Pannecouque C, Aquaro S, Perno CF, Naesens L, Witvrouw M, Heijtink R, De Clercq E, McGuigan C. Balzarini J, et al. Among authors: perno cf. FEBS Lett. 1997 Jun 30;410(2-3):324-8. doi: 10.1016/s0014-5793(97)00616-9. FEBS Lett. 1997. PMID: 9237655 Free article.

10

S-adenosylhomocysteine hydrolase inhibitors interfere with the replication of human immunodeficiency virus type 1 through inhibition of the LTR transactivation.

Daelemans D, Esté JA, Witvrouw M, Pannecouque C, Jonckheere H, Aquaro S, Perno CF, De Clercq E, Vandamme AM. Daelemans D, et al. Among authors: perno cf. Mol Pharmacol. 1997 Dec;52(6):1157-63. doi: 10.1124/mol.52.6.1157. Mol Pharmacol. 1997. PMID: 9396786

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