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Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.
van Beusekom B, Heidebrecht T, Adamopoulos A, Fish A, Pardon E, Steyaert J, Joosten RP, Perrakis A. van Beusekom B, et al. Among authors: perrakis a. Acta Crystallogr F Struct Biol Commun. 2018 Nov 1;74(Pt 11):690-695. doi: 10.1107/S2053230X18010282. Epub 2018 Oct 16. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 30387773 Free PMC article.
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.
De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. De Marco V, et al. Among authors: perrakis a. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19807-12. doi: 10.1073/pnas.0905281106. Epub 2009 Nov 11. Proc Natl Acad Sci U S A. 2009. PMID: 19906994 Free PMC article.
Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence.
Littler DR, Alvarez-Fernández M, Stein A, Hibbert RG, Heidebrecht T, Aloy P, Medema RH, Perrakis A. Littler DR, et al. Among authors: perrakis a. Nucleic Acids Res. 2010 Jul;38(13):4527-38. doi: 10.1093/nar/gkq194. Epub 2010 Mar 31. Nucleic Acids Res. 2010. PMID: 20360045 Free PMC article.
Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.
Hausmann J, Christodoulou E, Kasiem M, De Marco V, van Meeteren LA, Moolenaar WH, Axford D, Owen RL, Evans G, Perrakis A. Hausmann J, et al. Among authors: perrakis a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1130-5. doi: 10.1107/S1744309110032938. Epub 2010 Aug 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823545 Free PMC article.
Structural basis of substrate discrimination and integrin binding by autotaxin.
Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Hausmann J, et al. Among authors: perrakis a. Nat Struct Mol Biol. 2011 Feb;18(2):198-204. doi: 10.1038/nsmb.1980. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240271 Free PMC article.
Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.
Busso D, Peleg Y, Heidebrecht T, Romier C, Jacobovitch Y, Dantes A, Salim L, Troesch E, Schuetz A, Heinemann U, Folkers GE, Geerlof A, Wilmanns M, Polewacz A, Quedenau C, Büssow K, Adamson R, Blagova E, Walton J, Cartwright JL, Bird LE, Owens RJ, Berrow NS, Wilson KS, Sussman JL, Perrakis A, Celie PH. Busso D, et al. Among authors: perrakis a. J Struct Biol. 2011 Aug;175(2):159-70. doi: 10.1016/j.jsb.2011.03.004. Epub 2011 Mar 5. J Struct Biol. 2011. PMID: 21382497
Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS.
Monti MC, Cohen SX, Fish A, Winterwerp HH, Barendregt A, Friedhoff P, Perrakis A, Heck AJ, Sixma TK, van den Heuvel RH, Lebbink JH. Monti MC, et al. Among authors: perrakis a. Nucleic Acids Res. 2011 Oct;39(18):8052-64. doi: 10.1093/nar/gkr498. Epub 2011 Jul 6. Nucleic Acids Res. 2011. PMID: 21737427 Free PMC article.
A new generation of crystallographic validation tools for the protein data bank.
Read RJ, Adams PD, Arendall WB 3rd, Brunger AT, Emsley P, Joosten RP, Kleywegt GJ, Krissinel EB, Lütteke T, Otwinowski Z, Perrakis A, Richardson JS, Sheffler WH, Smith JL, Tickle IJ, Vriend G, Zwart PH. Read RJ, et al. Among authors: perrakis a. Structure. 2011 Oct 12;19(10):1395-412. doi: 10.1016/j.str.2011.08.006. Structure. 2011. PMID: 22000512 Free PMC article.
241 results