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The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase.
Heppler LN, Attarha S, Persaud R, Brown JI, Wang P, Petrova B, Tošić I, Burton FB, Flamand Y, Walker SR, Yeh JE, Zubarev RA, Gaetani M, Kanarek N, Page BDG, Frank DA. Heppler LN, et al. Among authors: persaud r. J Biol Chem. 2022 Feb;298(2):101531. doi: 10.1016/j.jbc.2021.101531. Epub 2021 Dec 23. J Biol Chem. 2022. PMID: 34953855 Free PMC article.
Longitudinal Analysis of Mpox Virus DNA Detectability From Multiple Specimen Types During Acute Illness: A Cohort Study.
Tan DHS, Pico Espinosa O, Matelski J, Khera SS, Qamar A, Persaud R, Hurst JR, Ly A, Lam J, Naghibosadat M, Christie N, Hasso M, Gough K, Taggart LR, Tan C, Ostrowski M, Ma H, Gray-Owen SD, Kozak R, Mishra S. Tan DHS, et al. Among authors: persaud r. Open Forum Infect Dis. 2024 Feb 7;11(2):ofae073. doi: 10.1093/ofid/ofae073. eCollection 2024 Feb. Open Forum Infect Dis. 2024. PMID: 38390463 Free PMC article.
Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses.
Jossi SE, Arcuri M, Alshayea A, Persaud RR, Marcial-Juárez E, Palmieri E, Di Benedetto R, Pérez-Toledo M, Pillaye J, Channell WM, Schager AE, Lamerton RE, Cook CN, Goodall M, Haneda T, Bäumler AJ, Jackson-Jones LH, Toellner KM, MacLennan CA, Henderson IR, Micoli F, Cunningham AF. Jossi SE, et al. Among authors: persaud rr. Front Immunol. 2023 Mar 23;14:1139329. doi: 10.3389/fimmu.2023.1139329. eCollection 2023. Front Immunol. 2023. PMID: 37033932 Free PMC article.
Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers.
Marcial-Juárez E, Pérez-Toledo M, Nayar S, Pipi E, Alshayea A, Persaud R, Jossi SE, Lamerton R, Barone F, Henderson IR, Cunningham AF. Marcial-Juárez E, et al. Among authors: persaud r. iScience. 2023 Mar 2;26(4):106310. doi: 10.1016/j.isci.2023.106310. eCollection 2023 Apr 21. iScience. 2023. PMID: 36950118 Free PMC article.
Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity.
Brown JI, Wang P, Wong AYL, Petrova B, Persaud R, Soukhtehzari S, Lopez McDonald M, Hanke D, Christensen J, Iliev P, Wang W, Everton DK, Williams KC, Frank DA, Kanarek N, Page BDG. Brown JI, et al. Among authors: persaud r. Metabolites. 2023 Jan 19;13(2):151. doi: 10.3390/metabo13020151. Metabolites. 2023. PMID: 36837770 Free PMC article.
183 results