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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 3
1990 1
1995 1
1998 1
2003 1
2004 2
2005 2
2006 1
2008 1
2009 5
2010 10
2011 13
2012 20
2013 26
2014 19
2015 20
2016 42
2017 56
2018 58
2019 73
2020 15
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337 results
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Personalized medicine to treat arrhythmias.
Roden DM. Roden DM. Curr Opin Pharmacol. 2014 Apr;15:61-7. doi: 10.1016/j.coph.2013.11.013. Epub 2013 Dec 22. Curr Opin Pharmacol. 2014. PMID: 24721655 Free PMC article. Review.
The efficacy of antiarrhythmic drug therapy is incomplete, with responses ranging from efficacy to no effect to severe adverse effects, including paradoxical drug-induced arrhythmia. Most antiarrhythmic drugs were developed at a time when the mechanisms underlying …
The efficacy of antiarrhythmic drug therapy is incomplete, with responses ranging from efficacy to no effect to severe adverse effect …
Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies.
Wu JC, Garg P, Yoshida Y, Yamanaka S, Gepstein L, Hulot JS, Knollmann BC, Schwartz PJ. Wu JC, et al. Circ Res. 2019 Aug 30;125(6):653-658. doi: 10.1161/CIRCRESAHA.119.315209. Epub 2019 Aug 29. Circ Res. 2019. PMID: 31465267 Review.
Long-QT syndrome, a frequently fatal inherited arrhythmia syndrome caused by genetic variants (congenital) or drugs (acquired), affects 1 in 2000 people worldwide. Its sentinel event is often sudden cardiac death, which makes preclinical diagnosis by genetic testing …
Long-QT syndrome, a frequently fatal inherited arrhythmia syndrome caused by genetic variants (congenital) or drugs (acquired), affec …
Dilated cardiomyopathy.
Schultheiss HP, Fairweather D, Caforio ALP, Escher F, Hershberger RE, Lipshultz SE, Liu PP, Matsumori A, Mazzanti A, McMurray J, Priori SG. Schultheiss HP, et al. Nat Rev Dis Primers. 2019 May 9;5(1):32. doi: 10.1038/s41572-019-0084-1. Nat Rev Dis Primers. 2019. PMID: 31073128 Free PMC article. Review.
As DCM eventually leads to impaired contractility, standard approaches to prevent or treat heart failure are the first-line treatment for patients with DCM. Cardiac resynchronization therapy and implantable cardioverter-defibrillators may be required to preve …
As DCM eventually leads to impaired contractility, standard approaches to prevent or treat heart failure are the first-line treatment …
Risk Stratification for Sudden Cardiac Death in Non-Ischaemic Dilated Cardiomyopathy.
Akhtar M, Elliott PM. Akhtar M, et al. Curr Cardiol Rep. 2019 Nov 25;21(12):155. doi: 10.1007/s11886-019-1236-3. Curr Cardiol Rep. 2019. PMID: 31768884 Free PMC article. Review.
The purpose of this article is to review the literature for other potential markers including serological, electrocardiographic, echocardiographic, cardiac magnetic resonance, ambulatory ECG and genetic data, to highlight other potential markers that may optimise risk stra …
The purpose of this article is to review the literature for other potential markers including serological, electrocardiographic, echocardiog …
The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for Patients on a Direct Oral Anticoagulant Who Need an Elective Surgery or Procedure: Design and Rationale.
Douketis JD, Spyropoulos AC, Anderson JM, Arnold DM, Bates SM, Blostein M, Carrier M, Caprini JA, Clark NP, Coppens M, Dentali F, Duncan J, Gross PL, Kassis J, Kowalski S, Lee AY, Le Gal G, Le Templier G, Li N, MacKay E, Shah V, Shivakumar S, Solymoss S, Spencer FA, Syed S, Tafur AJ, Vanassche T, Thiele T, Wu C, Yeo E, Schulman S. Douketis JD, et al. Thromb Haemost. 2017 Dec;117(12):2415-2424. doi: 10.1160/TH17-08-0553. Epub 2017 Dec 6. Thromb Haemost. 2017. PMID: 29212129 Clinical Trial.
The perioperative protocol accounts for DOAC type, patient's renal function and surgery/procedure-related bleeding risk. The primary study aim is to demonstrate the safety of the PAUSE protocol for the perioperative management of each DOAC. ...Conclusion The PAUSE study ha …
The perioperative protocol accounts for DOAC type, patient's renal function and surgery/procedure-related bleeding risk. The primary …
Noninvasive Cardioablation.
Refaat MM, Zakka P, Youssef B, Zeidan YH, Geara F, Al-Ahmad A. Refaat MM, et al. Card Electrophysiol Clin. 2019 Sep;11(3):481-485. doi: 10.1016/j.ccep.2019.05.008. Card Electrophysiol Clin. 2019. PMID: 31400872 Review.
Because of its high precision and target conformity, it can deliver a high dose of radiation to a specific area in a tissue without significantly affecting nearby tissues. It is being actively studied and even used in therapy for atrial fibrillation and ventricular …
Because of its high precision and target conformity, it can deliver a high dose of radiation to a specific area in a tissue without s …
Genetics of Dilated Cardiomyopathy: Clinical Implications.
Paldino A, De Angelis G, Merlo M, Gigli M, Dal Ferro M, Severini GM, Mestroni L, Sinagra G. Paldino A, et al. Curr Cardiol Rep. 2018 Aug 13;20(10):83. doi: 10.1007/s11886-018-1030-7. Curr Cardiol Rep. 2018. PMID: 30105555 Review.
The recent discoveries and future research in the field of genotype-phenotype correlation may lead to a more personalized management of the mutation carriers towards the application of precision medicine in DCM....
The recent discoveries and future research in the field of genotype-phenotype correlation may lead to a more personalized management …
Looking back and thinking forwards - 15 years of cardiology and cardiovascular research.
Kalman JM, Lavandero S, Mahfoud F, Nahrendorf M, Yacoub MH, Zhao D. Kalman JM, et al. Nat Rev Cardiol. 2019 Nov;16(11):651-660. doi: 10.1038/s41569-019-0261-7. Epub 2019 Sep 30. Nat Rev Cardiol. 2019. PMID: 31570832 Review.
Several practice-changing breakthroughs are described, including advances in procedural techniques to treat arrhythmias and hypertension and the development of novel therapeutic strategies to treat heart failure and pulmonary arterial hypertension, as well as …
Several practice-changing breakthroughs are described, including advances in procedural techniques to treat arrhythmias and hy …
Multi-ethnic genome-wide association study for atrial fibrillation.
Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT. Roselli C, et al. Nat Genet. 2018 Jun 11;50(9):1225-1233. doi: 10.1038/s41588-018-0133-9. Nat Genet. 2018. PMID: 29892015 Free PMC article.
The identified loci implicate genes enriched within cardiac developmental, electrophysiological, contractile and structural pathways. These results extend our understanding of the biological pathways underlying AF and may facilitate the development of therapeutics f …
The identified loci implicate genes enriched within cardiac developmental, electrophysiological, contractile and structural pathways. …
Pharmacogenetics in Cardiovascular Medicine.
Weeke PE. Weeke PE. Adv Pharmacol. 2018;83:333-360. doi: 10.1016/bs.apha.2018.04.002. Adv Pharmacol. 2018. PMID: 29801582 Review.
Fueled by advancements and multidisciplinary collaboration across disciplines such as genetics, bioinformatics, and basic research, the vision of personalized medicine, rather than a one-size-fits-all approach, may be within reach. ...To date, a multitude of studies …
Fueled by advancements and multidisciplinary collaboration across disciplines such as genetics, bioinformatics, and basic research, the visi …
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