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Allosteric activation of coagulation factor VIIa.
Persson E, Olsen OH. Persson E, et al. Front Biosci (Landmark Ed). 2011 Jun 1;16(8):3156-63. doi: 10.2741/3903. Front Biosci (Landmark Ed). 2011. PMID: 21622226 Free article. Review.
Assignment of molecular properties of a superactive coagulation factor VIIa variant to individual amino acid changes.
Persson E, Olsen OH. Persson E, et al. Eur J Biochem. 2002 Dec;269(23):5950-5. doi: 10.1046/j.1432-1033.2002.03323.x. Eur J Biochem. 2002. PMID: 12444984 Free article.
The most active factor VIIa (FVIIa) variants identified to date carry concurrent substitutions at positions 158, 296 and 298 with the intention of generating a thrombin-mimicking motif, optionally combined with additional replacements within the protease domain [Persson, …
The most active factor VIIa (FVIIa) variants identified to date carry concurrent substitutions at positions 158, 296 and 298 with the intent …
532 results