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Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera.
Atkinson SC, Dogovski C, Newman J, Dobson RC, Perugini MA. Atkinson SC, et al. Among authors: perugini ma. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1537-41. doi: 10.1107/S1744309111038395. Epub 2011 Nov 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22139160 Free PMC article.
The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.
Luke MR, Houghton F, Perugini MA, Gleeson PA. Luke MR, et al. Among authors: perugini ma. Biochem J. 2005 Jun 15;388(Pt 3):835-41. doi: 10.1042/BJ20041810. Biochem J. 2005. PMID: 15654769 Free PMC article.
Insight into the self-association of key enzymes from pathogenic species.
Perugini MA, Griffin MD, Smith BJ, Webb LE, Davis AJ, Handman E, Gerrard JA. Perugini MA, et al. Eur Biophys J. 2005 Jul;34(5):469-76. doi: 10.1007/s00249-005-0491-y. Epub 2005 Jun 25. Eur Biophys J. 2005. PMID: 15981001
Dihydrodipicolinate synthase from Thermotoga maritima.
Pearce FG, Perugini MA, McKerchar HJ, Gerrard JA. Pearce FG, et al. Among authors: perugini ma. Biochem J. 2006 Dec 1;400(2):359-66. doi: 10.1042/BJ20060771. Biochem J. 2006. PMID: 16872276 Free PMC article.
Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms.
Kedzierski L, Malby RL, Smith BJ, Perugini MA, Hodder AN, Ilg T, Colman PM, Handman E. Kedzierski L, et al. Among authors: perugini ma. J Mol Biol. 2006 Oct 13;363(1):215-27. doi: 10.1016/j.jmb.2006.08.023. Epub 2006 Aug 12. J Mol Biol. 2006. PMID: 16963079
Structural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein E.
Gunzburg MJ, Perugini MA, Howlett GJ. Gunzburg MJ, et al. Among authors: perugini ma. J Biol Chem. 2007 Dec 7;282(49):35831-41. doi: 10.1074/jbc.M706425200. Epub 2007 Oct 4. J Biol Chem. 2007. PMID: 17916554
Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways.
Griffin MD, Mok ML, Wilson LM, Pham CL, Waddington LJ, Perugini MA, Howlett GJ. Griffin MD, et al. Among authors: perugini ma. J Mol Biol. 2008 Jan 4;375(1):240-56. doi: 10.1016/j.jmb.2007.10.038. Epub 2007 Oct 22. J Mol Biol. 2008. PMID: 18005990
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?
Mitsakos V, Dobson RC, Pearce FG, Devenish SR, Evans GL, Burgess BR, Perugini MA, Gerrard JA, Hutton CA. Mitsakos V, et al. Among authors: perugini ma. Bioorg Med Chem Lett. 2008 Jan 15;18(2):842-4. doi: 10.1016/j.bmcl.2007.11.026. Epub 2007 Nov 13. Bioorg Med Chem Lett. 2008. PMID: 18054225
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC. Kefala G, et al. Among authors: perugini ma. Biochem J. 2008 Apr 15;411(2):351-60. doi: 10.1042/BJ20071360. Biochem J. 2008. PMID: 18062777
The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum.
Dobson RC, Atkinson SC, Gorman MA, Newman JM, Parker MW, Perugini MA. Dobson RC, et al. Among authors: perugini ma. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Mar 1;64(Pt 3):206-8. doi: 10.1107/S1744309108002819. Epub 2008 Feb 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18323610 Free PMC article.
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