Perumal D - Search Results

1

YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells.

Bora-Singhal N, Nguyen J, Schaal C, Perumal D, Singh S, Coppola D, Chellappan S. Bora-Singhal N, et al. Among authors: perumal d. Stem Cells. 2015 Jun;33(6):1705-18. doi: 10.1002/stem.1993. Stem Cells. 2015. PMID: 25754111 Free PMC article.

2

A novel five gene signature derived from stem-like side population cells predicts overall and recurrence-free survival in NSCLC.

Perumal D, Singh S, Yoder SJ, Bloom GC, Chellappan SP. Perumal D, et al. PLoS One. 2012;7(8):e43589. doi: 10.1371/journal.pone.0043589. Epub 2012 Aug 29. PLoS One. 2012. PMID: 22952714 Free PMC article.

3

Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner.

Nair S, Bora-Singhal N, Perumal D, Chellappan S. Nair S, et al. Among authors: perumal d. Mol Cancer. 2014 Jul 16;13:173. doi: 10.1186/1476-4598-13-173. Mol Cancer. 2014. PMID: 25028095 Free PMC article.

4

Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ β-arrestin-1 dependent manner in NSCLC.

Perumal D, Pillai S, Nguyen J, Schaal C, Coppola D, Chellappan SP. Perumal D, et al. Oncotarget. 2014 Nov 15;5(21):10486-502. doi: 10.18632/oncotarget.2395. Oncotarget. 2014. PMID: 25401222 Free PMC article.

5

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.

Bora-Singhal N, Perumal D, Nguyen J, Chellappan S. Bora-Singhal N, et al. Among authors: perumal d. Neoplasia. 2015 Jul;17(7):538-51. doi: 10.1016/j.neo.2015.07.001. Neoplasia. 2015. PMID: 26297432 Free PMC article.

6

Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.

Kotini AG, Chang CJ, Chow A, Yuan H, Ho TC, Wang T, Vora S, Solovyov A, Husser C, Olszewska M, Teruya-Feldstein J, Perumal D, Klimek VM, Spyridonidis A, Rampal RK, Silverman L, Reddy EP, Papaemmanuil E, Parekh S, Greenbaum BD, Leslie CS, Kharas MG, Papapetrou EP. Kotini AG, et al. Among authors: perumal d. Cell Stem Cell. 2017 Mar 2;20(3):315-328.e7. doi: 10.1016/j.stem.2017.01.009. Epub 2017 Feb 16. Cell Stem Cell. 2017. PMID: 28215825 Free PMC article.

7

High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma.

Kuo PY, Leshchenko VV, Fazzari MJ, Perumal D, Gellen T, He T, Iqbal J, Baumgartner-Wennerholm S, Nygren L, Zhang F, Zhang W, Suh KS, Goy A, Yang DT, Chan WC, Kahl BS, Verma AK, Gascoyne RD, Kimby E, Sander B, Ye BH, Melnick AM, Parekh S. Kuo PY, et al. Among authors: perumal d. Oncogene. 2015 Mar 5;34(10):1231-40. doi: 10.1038/onc.2014.44. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681958 Free PMC article.

8

Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma.

Perumal D, Kuo PY, Leshchenko VV, Jiang Z, Divakar SK, Cho HJ, Chari A, Brody J, Reddy MV, Zhang W, Reddy EP, Jagannath S, Parekh S. Perumal D, et al. Cancer Res. 2016 Mar 1;76(5):1225-36. doi: 10.1158/0008-5472.CAN-15-2934. Epub 2016 Feb 12. Cancer Res. 2016. PMID: 26873845 Free PMC article.

9

Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.

Divakar SK, Ramana Reddy MV, Cosenza SC, Baker SJ, Perumal D, Antonelli AC, Brody J, Akula B, Parekh S, Reddy EP. Divakar SK, et al. Among authors: perumal d. Leukemia. 2016 Jan;30(1):86-93. doi: 10.1038/leu.2015.185. Epub 2015 Jul 15. Leukemia. 2016. PMID: 26174628 Free PMC article.

10

Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma.

Laganà A, Perumal D, Melnekoff D, Readhead B, Kidd BA, Leshchenko V, Kuo PY, Keats J, DeRome M, Yesil J, Auclair D, Lonial S, Chari A, Cho HJ, Barlogie B, Jagannath S, Dudley JT, Parekh S. Laganà A, et al. Among authors: perumal d. Leukemia. 2018 Jan;32(1):120-130. doi: 10.1038/leu.2017.197. Epub 2017 Jun 23. Leukemia. 2018. PMID: 28642592

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