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BCL-2: pro-or anti-oxidant?
Chen ZX, Pervaiz S. Chen ZX, et al. Among authors: pervaiz s. Front Biosci (Elite Ed). 2009 Jun 1;1:263-8. doi: 10.2741/s13. Front Biosci (Elite Ed). 2009. PMID: 19482643 Review.
Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: an hypothesis.
Clément MV, Pervaiz S. Clément MV, et al. Among authors: pervaiz s. Free Radic Res. 1999 Apr;30(4):247-52. doi: 10.1080/10715769900300271. Free Radic Res. 1999. PMID: 10230803 Review.
Hence, it is equally important to decipher how ROI influence the response of cells to signals that activate cell death pathway(s). ...
Hence, it is equally important to decipher how ROI influence the response of cells to signals that activate cell death pathway(s). .. …
Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cells.
Pervaiz S, Seyed MA, Hirpara JL, Clément MV, Loh KW. Pervaiz S, et al. Blood. 1999 Jun 15;93(12):4096-108. Blood. 1999. PMID: 10361106
Because pMC540 is a mixture of photoproducts, we set out to purify the biologically active component(s) from this mixture and to investigate their ability to directly activate intracellular caspases and/or trigger mitochondrial events associated with apoptosis. ...
Because pMC540 is a mixture of photoproducts, we set out to purify the biologically active component(s) from this mixture and to inve …
Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells.
Hirpara JL, Seyed MA, Loh KW, Dong H, Kini RM, Pervaiz S. Hirpara JL, et al. Among authors: pervaiz s. Blood. 2000 Mar 1;95(5):1773-80. Blood. 2000. PMID: 10688837
Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells.
Hirpara JL, Clément MV, Pervaiz S. Hirpara JL, et al. Among authors: pervaiz s. J Biol Chem. 2001 Jan 5;276(1):514-21. doi: 10.1074/jbc.M004687200. J Biol Chem. 2001. PMID: 11016925 Retracted.
Reactive oxygen-dependent production of novel photochemotherapeutic agents.
Pervaiz S. Pervaiz S. FASEB J. 2001 Mar;15(3):612-7. doi: 10.1096/fj.00-0555rev. FASEB J. 2001. PMID: 11259379 Review.
-Pervaiz, S. Reactive oxygen-dependent production of novel photochemotherapeutic agents....
-Pervaiz, S. Reactive oxygen-dependent production of novel photochemotherapeutic agents....
Resveratrol--from the bottle to the bedside?
Pervaiz S. Pervaiz S. Leuk Lymphoma. 2001 Feb;40(5-6):491-8. doi: 10.3109/10428190109097648. Leuk Lymphoma. 2001. PMID: 11426522 Review.
Not only has its role as an anti-cancer agent been corroborated, but the precise mechanism(s) of the anti-cancer activity of resveratrol is/are being elucidated. ...
Not only has its role as an anti-cancer agent been corroborated, but the precise mechanism(s) of the anti-cancer activity of resverat …
Activation of the RacGTPase inhibits apoptosis in human tumor cells.
Pervaiz S, Cao J, Chao OS, Chin YY, Clément MV. Pervaiz S, et al. Oncogene. 2001 Sep 27;20(43):6263-8. doi: 10.1038/sj.onc.1204840. Oncogene. 2001. PMID: 11593437
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