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Regulation of gli activity by all-trans retinoic acid in mouse keratinocytes.
Goyette P, Allan D, Peschard P, Chen CF, Wang W, Lohnes D. Goyette P, et al. Cancer Res. 2000 Oct 1;60(19):5386-9. Cancer Res. 2000. PMID: 11034076
The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis.
Saucier C, Khoury H, Lai KM, Peschard P, Dankort D, Naujokas MA, Holash J, Yancopoulos GD, Muller WJ, Pawson T, Park M. Saucier C, et al. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2345-50. doi: 10.1073/pnas.0308065101. Proc Natl Acad Sci U S A. 2004. PMID: 14983012 Free PMC article.
A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.
Peschard P, Ishiyama N, Lin T, Lipkowitz S, Park M. Peschard P, et al. J Biol Chem. 2004 Jul 9;279(28):29565-71. doi: 10.1074/jbc.M403954200. Epub 2004 Apr 29. J Biol Chem. 2004. PMID: 15123609
Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.
Abella JV, Peschard P, Naujokas MA, Lin T, Saucier C, Urbé S, Park M. Abella JV, et al. Mol Cell Biol. 2005 Nov;25(21):9632-45. doi: 10.1128/MCB.25.21.9632-9645.2005. Mol Cell Biol. 2005. PMID: 16227611 Free PMC article.
From Tpr-Met to Met, tumorigenesis and tubes.
Peschard P, Park M. Peschard P, et al. Oncogene. 2007 Feb 26;26(9):1276-85. doi: 10.1038/sj.onc.1210201. Oncogene. 2007. PMID: 17322912 Review.
Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway.
Mak HH, Peschard P, Lin T, Naujokas MA, Zuo D, Park M. Mak HH, et al. Among authors: peschard p. Oncogene. 2007 Nov 8;26(51):7213-21. doi: 10.1038/sj.onc.1210522. Epub 2007 May 28. Oncogene. 2007. PMID: 17533376
Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase.
Kozlov G, Peschard P, Zimmerman B, Lin T, Moldoveanu T, Mansur-Azzam N, Gehring K, Park M. Kozlov G, et al. Among authors: peschard p. J Biol Chem. 2007 Sep 14;282(37):27547-55. doi: 10.1074/jbc.M703333200. Epub 2007 Jul 16. J Biol Chem. 2007. PMID: 17635922 Free article.
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