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First fatty acylated dipeptides to affect muscarinic receptor ligand binding.
Krishnan V, Pham WN, Messer WS Jr, Peseckis SM. Krishnan V, et al. Among authors: peseckis sm. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3363-8. doi: 10.1016/s0960-894x(99)00604-6. Bioorg Med Chem Lett. 1999. PMID: 10612600
Fatty acylation enhances cellular localization of dansylated phenylalanines.
Dudley RW, Slotterbeck BD, McInerney MF, Peseckis SM. Dudley RW, et al. Among authors: peseckis sm. Mol Cell Biochem. 2011 Jan;346(1-2):81-7. doi: 10.1007/s11010-010-0593-4. Epub 2010 Oct 8. Mol Cell Biochem. 2011. PMID: 20931354
Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors.
Messer WS Jr, Rajeswaran WG, Cao Y, Zhang HJ, el-Assadi AA, Dockery C, Liske J, O'Brien J, Williams FE, Huang XP, Wroblewski ME, Nagy PI, Peseckis SM. Messer WS Jr, et al. Among authors: peseckis sm. Pharm Acta Helv. 2000 Mar;74(2-3):135-40. doi: 10.1016/s0031-6865(99)00026-6. Pharm Acta Helv. 2000. PMID: 10812950
Pharmacological characterization of human m1 muscarinic acetylcholine receptors with double mutations at the junction of TM VI and the third extracellular domain.
Huang XP, Williams FE, Peseckis SM, Messer WS Jr. Huang XP, et al. Among authors: peseckis sm. J Pharmacol Exp Ther. 1998 Sep;286(3):1129-39. J Pharmacol Exp Ther. 1998. PMID: 9732369
Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1 muscarinic receptors.
Huang XP, Nagy PI, Williams FE, Peseckis SM, Messer WS Jr. Huang XP, et al. Among authors: peseckis sm. Br J Pharmacol. 1999 Feb;126(3):735-45. doi: 10.1038/sj.bjp.0702301. Br J Pharmacol. 1999. PMID: 10188986 Free PMC article.
Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.
Huang XP, Williams FE, Peseckis SM, Messer WS Jr. Huang XP, et al. Among authors: peseckis sm. Mol Pharmacol. 1999 Oct;56(4):775-83. Mol Pharmacol. 1999. PMID: 10496961
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