Pestell RG - Search Results

1

Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism.

Ertel A, Tsirigos A, Whitaker-Menezes D, Birbe RC, Pavlides S, Martinez-Outschoorn UE, Pestell RG, Howell A, Sotgia F, Lisanti MP. Ertel A, et al. Among authors: pestell rg. Cell Cycle. 2012 Jan 15;11(2):253-63. doi: 10.4161/cc.11.2.19006. Epub 2012 Jan 15. Cell Cycle. 2012. PMID: 22234241 Free PMC article.

2

p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.

Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. Engelman JA, et al. Among authors: pestell rg. J Biol Chem. 1999 Nov 5;274(45):32333-41. doi: 10.1074/jbc.274.45.32333. J Biol Chem. 1999. PMID: 10542274 Free article.

3

Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.

Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Razani B, et al. Among authors: pestell rg. Biochemistry. 2000 Nov 14;39(45):13916-24. doi: 10.1021/bi001489b. Biochemistry. 2000. PMID: 11076533

4

Caveolins in cholesterol trafficking and signal transduction: implications for human disease.

Schlegel A, Pestell RG, Lisanti MP. Schlegel A, et al. Among authors: pestell rg. Front Biosci. 2000 Dec 1;5:D929-37. doi: 10.2741/schlegel. Front Biosci. 2000. PMID: 11102315 Review.

5

Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism.

Park DS, Razani B, Lasorella A, Schreiber-Agus N, Pestell RG, Iavarone A, Lisanti MP. Park DS, et al. Among authors: pestell rg. Biochemistry. 2001 Mar 20;40(11):3354-62. doi: 10.1021/bi002787b. Biochemistry. 2001. PMID: 11258956

6

Ligand-independent activation of oestrogen receptor alpha by caveolin-1.

Schlegel A, Wang C, Pestell RG, Lisanti MP. Schlegel A, et al. Among authors: pestell rg. Biochem J. 2001 Oct 1;359(Pt 1):203-10. doi: 10.1042/0264-6021:3590203. Biochem J. 2001. PMID: 11563984 Free PMC article.

7

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.

Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Lee H, et al. Among authors: pestell rg. Am J Pathol. 2002 Oct;161(4):1357-69. doi: 10.1016/S0002-9440(10)64412-4. Am J Pathol. 2002. PMID: 12368209 Free PMC article.

8

Acetylation in hormone signaling and the cell cycle.

Fu M, Wang C, Wang J, Zafonte BT, Lisanti MP, Pestell RG. Fu M, et al. Among authors: pestell rg. Cytokine Growth Factor Rev. 2002 Jun;13(3):259-76. doi: 10.1016/s1359-6101(02)00003-5. Cytokine Growth Factor Rev. 2002. PMID: 12486878 Review.

9

Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.

Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: pestell rg. Mol Biol Cell. 2003 Mar;14(3):1027-42. doi: 10.1091/mbc.e02-08-0503. Mol Biol Cell. 2003. PMID: 12631721 Free PMC article.

10

Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization.

Iyengar P, Combs TP, Shah SJ, Gouon-Evans V, Pollard JW, Albanese C, Flanagan L, Tenniswood MP, Guha C, Lisanti MP, Pestell RG, Scherer PE. Iyengar P, et al. Among authors: pestell rg. Oncogene. 2003 Sep 25;22(41):6408-23. doi: 10.1038/sj.onc.1206737. Oncogene. 2003. PMID: 14508521

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