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Toxin-antitoxin systems in bacterial growth arrest and persistence.
Page R, Peti W. Page R, et al. Among authors: peti w. Nat Chem Biol. 2016 Apr;12(4):208-14. doi: 10.1038/nchembio.2044. Nat Chem Biol. 2016. PMID: 26991085 Review.
Detailed structural characterization of unbound protein phosphatase 1 inhibitors.
Dancheck B, Nairn AC, Peti W. Dancheck B, et al. Among authors: peti w. Biochemistry. 2008 Nov 25;47(47):12346-56. doi: 10.1021/bi801308y. Biochemistry. 2008. PMID: 18954090 Free PMC article.
Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors.
Kelker MS, Page R, Peti W. Kelker MS, et al. Among authors: peti w. J Mol Biol. 2009 Jan 9;385(1):11-21. doi: 10.1016/j.jmb.2008.10.053. Epub 2008 Nov 1. J Mol Biol. 2009. PMID: 18992256 Free PMC article.
Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties.
Brown BL, Grigoriu S, Kim Y, Arruda JM, Davenport A, Wood TK, Peti W, Page R. Brown BL, et al. Among authors: peti w. PLoS Pathog. 2009 Dec;5(12):e1000706. doi: 10.1371/journal.ppat.1000706. Epub 2009 Dec 24. PLoS Pathog. 2009. PMID: 20041169 Free PMC article.
Escherichia coli toxin/antitoxin pair MqsR/MqsA regulate toxin CspD.
Kim Y, Wang X, Zhang XS, Grigoriu S, Page R, Peti W, Wood TK. Kim Y, et al. Among authors: peti w. Environ Microbiol. 2010 May;12(5):1105-21. doi: 10.1111/j.1462-2920.2009.02147.x. Epub 2010 Jan 26. Environ Microbiol. 2010. PMID: 20105222 Free PMC article.
Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Ragusa MJ, Dancheck B, Critton DA, Nairn AC, Page R, Peti W. Ragusa MJ, et al. Among authors: peti w. Nat Struct Mol Biol. 2010 Apr;17(4):459-64. doi: 10.1038/nsmb.1786. Epub 2010 Mar 21. Nat Struct Mol Biol. 2010. PMID: 20305656 Free PMC article.
Structure of the Escherichia coli antitoxin MqsA (YgiT/b3021) bound to its gene promoter reveals extensive domain rearrangements and the specificity of transcriptional regulation.
Brown BL, Wood TK, Peti W, Page R. Brown BL, et al. Among authors: peti w. J Biol Chem. 2011 Jan 21;286(3):2285-96. doi: 10.1074/jbc.M110.172643. Epub 2010 Nov 9. J Biol Chem. 2011. PMID: 21068382 Free PMC article.
Structural signature of the MYPT1-PP1 interaction.
Pinheiro AS, Marsh JA, Forman-Kay JD, Peti W. Pinheiro AS, et al. Among authors: peti w. J Am Chem Soc. 2011 Jan 12;133(1):73-80. doi: 10.1021/ja107810r. Epub 2010 Dec 10. J Am Chem Soc. 2011. PMID: 21142030 Free PMC article.
Antitoxin MqsA helps mediate the bacterial general stress response.
Wang X, Kim Y, Hong SH, Ma Q, Brown BL, Pu M, Tarone AM, Benedik MJ, Peti W, Page R, Wood TK. Wang X, et al. Among authors: peti w. Nat Chem Biol. 2011 Jun;7(6):359-66. doi: 10.1038/nchembio.560. Epub 2011 Apr 24. Nat Chem Biol. 2011. PMID: 21516113 Free PMC article.
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