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IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma.
Frederiksen KS, Lundsgaard D, Freeman JA, Hughes SD, Holm TL, Skrumsager BK, Petri A, Hansen LT, McArthur GA, Davis ID, Skak K. Frederiksen KS, et al. Among authors: petri a. Cancer Immunol Immunother. 2008 Oct;57(10):1439-49. doi: 10.1007/s00262-008-0479-4. Epub 2008 Feb 20. Cancer Immunol Immunother. 2008. PMID: 18286285 Free PMC article. Clinical Trial.
LNA-mediated microRNA silencing in non-human primates.
Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, Obad S, Lindholm M, Hedtjärn M, Hansen HF, Berger U, Gullans S, Kearney P, Sarnow P, Straarup EM, Kauppinen S. Elmén J, et al. Among authors: petri a. Nature. 2008 Apr 17;452(7189):896-9. doi: 10.1038/nature06783. Epub 2008 Mar 26. Nature. 2008. PMID: 18368051
Silencing of microRNA families by seed-targeting tiny LNAs.
Obad S, dos Santos CO, Petri A, Heidenblad M, Broom O, Ruse C, Fu C, Lindow M, Stenvang J, Straarup EM, Hansen HF, Koch T, Pappin D, Hannon GJ, Kauppinen S. Obad S, et al. Among authors: petri a. Nat Genet. 2011 Mar 20;43(4):371-8. doi: 10.1038/ng.786. Nat Genet. 2011. PMID: 21423181 Free PMC article.
Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice.
Garchow BG, Bartulos Encinas O, Leung YT, Tsao PY, Eisenberg RA, Caricchio R, Obad S, Petri A, Kauppinen S, Kiriakidou M. Garchow BG, et al. Among authors: petri a. EMBO Mol Med. 2011 Oct;3(10):605-15. doi: 10.1002/emmm.201100171. Epub 2011 Sep 1. EMBO Mol Med. 2011. PMID: 21882343 Free PMC article.
Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR.
Rottiers V, Obad S, Petri A, McGarrah R, Lindholm MW, Black JC, Sinha S, Goody RJ, Lawrence MS, deLemos AS, Hansen HF, Whittaker S, Henry S, Brookes R, Najafi-Shoushtari SH, Chung RT, Whetstine JR, Gerszten RE, Kauppinen S, Näär AM. Rottiers V, et al. Among authors: petri a. Sci Transl Med. 2013 Nov 20;5(212):212ra162. doi: 10.1126/scitranslmed.3006840. Sci Transl Med. 2013. PMID: 24259050 Free PMC article.
247 results