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mTOR, translation initiation and cancer.
Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N. Mamane Y, et al. Oncogene. 2006 Oct 16;25(48):6416-22. doi: 10.1038/sj.onc.1209888. Oncogene. 2006. PMID: 17041626 Review.
Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling.
Kaur S, Lal L, Sassano A, Majchrzak-Kita B, Srikanth M, Baker DP, Petroulakis E, Hay N, Sonenberg N, Fish EN, Platanias LC. Kaur S, et al. J Biol Chem. 2007 Jan 19;282(3):1757-68. doi: 10.1074/jbc.M607365200. Epub 2006 Nov 17. J Biol Chem. 2007. PMID: 17114181
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.
Lee CH, Inoki K, Karbowniczek M, Petroulakis E, Sonenberg N, Henske EP, Guan KL. Lee CH, et al. EMBO J. 2007 Nov 28;26(23):4812-23. doi: 10.1038/sj.emboj.7601900. Epub 2007 Oct 25. EMBO J. 2007. PMID: 17962806 Free PMC article.
Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.
Ohanna M, Sobering AK, Lapointe T, Lorenzo L, Praud C, Petroulakis E, Sonenberg N, Kelly PA, Sotiropoulos A, Pende M. Ohanna M, et al. Nat Cell Biol. 2005 Mar;7(3):286-94. doi: 10.1038/ncb1231. Epub 2005 Feb 20. Nat Cell Biol. 2005. PMID: 15723049
Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase.
Martineau Y, Wang X, Alain T, Petroulakis E, Shahbazian D, Fabre B, Bousquet-Dubouch MP, Monsarrat B, Pyronnet S, Sonenberg N. Martineau Y, et al. Among authors: petroulakis e. Mol Cell Biol. 2014 Mar;34(6):1046-53. doi: 10.1128/MCB.01079-13. Epub 2014 Jan 6. Mol Cell Biol. 2014. PMID: 24396066 Free PMC article.
La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
Fonseca BD, Zakaria C, Jia JJ, Graber TE, Svitkin Y, Tahmasebi S, Healy D, Hoang HD, Jensen JM, Diao IT, Lussier A, Dajadian C, Padmanabhan N, Wang W, Matta-Camacho E, Hearnden J, Smith EM, Tsukumo Y, Yanagiya A, Morita M, Petroulakis E, González JL, Hernández G, Alain T, Damgaard CK. Fonseca BD, et al. Among authors: petroulakis e. J Biol Chem. 2015 Jun 26;290(26):15996-6020. doi: 10.1074/jbc.M114.621730. Epub 2015 May 4. J Biol Chem. 2015. PMID: 25940091 Free PMC article.
Multifaceted regulation of somatic cell reprogramming by mRNA translational control.
Tahmasebi S, Alain T, Rajasekhar VK, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Ghorbani M, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, Kim K, Yang XJ, Sonenberg N. Tahmasebi S, et al. Among authors: petroulakis e. Cell Stem Cell. 2014 May 1;14(5):606-16. doi: 10.1016/j.stem.2014.02.005. Epub 2014 Mar 13. Cell Stem Cell. 2014. PMID: 24630793 Free article.
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.
Furic L, Rong L, Larsson O, Koumakpayi IH, Yoshida K, Brueschke A, Petroulakis E, Robichaud N, Pollak M, Gaboury LA, Pandolfi PP, Saad F, Sonenberg N. Furic L, et al. Among authors: petroulakis e. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14134-9. doi: 10.1073/pnas.1005320107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679199 Free PMC article.
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Dowling RJ, Topisirovic I, Alain T, Bidinosti M, Fonseca BD, Petroulakis E, Wang X, Larsson O, Selvaraj A, Liu Y, Kozma SC, Thomas G, Sonenberg N. Dowling RJ, et al. Among authors: petroulakis e. Science. 2010 May 28;328(5982):1172-6. doi: 10.1126/science.1187532. Science. 2010. PMID: 20508131 Free PMC article.
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