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Binase cleaves cellular noncoding RNAs and affects coding mRNAs.
Mitkevich VA, Tchurikov NA, Zelenikhin PV, Petrushanko IY, Makarov AA, Ilinskaya ON. Mitkevich VA, et al. FEBS J. 2010 Jan;277(1):186-96. doi: 10.1111/j.1742-4658.2009.07471.x. Epub 2009 Nov 26. FEBS J. 2010. PMID: 19968715
Binase induces apoptosis of transformed myeloid cells and does not induce T-cell immune response.
Ilinskaya ON, Zelenikhin PV, Petrushanko IY, Mitkevich VA, Prassolov VS, Makarov AA. Ilinskaya ON, et al. Biochem Biophys Res Commun. 2007 Oct 5;361(4):1000-5. doi: 10.1016/j.bbrc.2007.07.143. Epub 2007 Aug 3. Biochem Biophys Res Commun. 2007. PMID: 17689490
Oncogenic c-kit transcript is a target for binase.
Mitkevich VA, Petrushanko IY, Kretova OV, Zelenikhin PV, Prassolov VS, Tchurikov NA, Ilinskaya ON, Makarov AA. Mitkevich VA, et al. Cell Cycle. 2010 Jul 1;9(13):2674-8. doi: 10.4161/cc.9.13.12150. Cell Cycle. 2010. PMID: 20581458
Sensitivity of acute myeloid leukemia Kasumi-1 cells to binase toxic action depends on the expression of KIT and АML1-ETO oncogenes.
Mitkevich VA, Petrushanko IY, Spirin PV, Fedorova TV, Kretova OV, Tchurikov NA, Prassolov VS, Ilinskaya ON, Makarov AA. Mitkevich VA, et al. Cell Cycle. 2011 Dec 1;10(23):4090-7. doi: 10.4161/cc.10.23.18210. Epub 2011 Dec 1. Cell Cycle. 2011. PMID: 22101339
Ribonuclease binase apoptotic signature in leukemic Kasumi-1 cells.
Mitkevich VA, Kretova OV, Petrushanko IY, Burnysheva KM, Sosin DV, Simonenko OV, Ilinskaya ON, Tchurikov NA, Makarov AA. Mitkevich VA, et al. Biochimie. 2013 Jun;95(6):1344-9. doi: 10.1016/j.biochi.2013.02.016. Epub 2013 Mar 13. Biochimie. 2013. PMID: 23499289
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Mironova NL, Petrushanko IY, Patutina OA, Sen'kova AV, Simonenko OV, Mitkevich VA, Markov OV, Zenkova MA, Makarov AA. Mironova NL, et al. Cell Cycle. 2013 Jul 1;12(13):2120-31. doi: 10.4161/cc.25164. Epub 2013 Jun 10. Cell Cycle. 2013. PMID: 23759588 Free PMC article.
Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells.
Mitkevich VA, Petrushanko IY, Yegorov YE, Simonenko OV, Vishnyakova KS, Kulikova AA, Tsvetkov PO, Makarov AA, Kozin SA. Mitkevich VA, et al. Cell Death Dis. 2013 Nov 28;4(11):e939. doi: 10.1038/cddis.2013.492. Cell Death Dis. 2013. PMID: 24287700 Free PMC article. No abstract available.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Sen'kova AV, Mironova NL, Patutina OA, Mitkevich VA, Markov OV, Petrushanko IY, Burnysheva KM, Zenkova MA, Makarov AA. Sen'kova AV, et al. Biochimie. 2014 Jun;101:256-9. doi: 10.1016/j.biochi.2014.02.006. Epub 2014 Feb 22. Biochimie. 2014. PMID: 24565811
Binding of ouabain and marinobufagenin leads to different structural changes in Na,K-ATPase and depends on the enzyme conformation.
Klimanova EA, Petrushanko IY, Mitkevich VA, Anashkina AA, Orlov SN, Makarov AA, Lopina OD. Klimanova EA, et al. FEBS Lett. 2015 Sep 14;589(19 Pt B):2668-74. doi: 10.1016/j.febslet.2015.08.011. Epub 2015 Aug 20. FEBS Lett. 2015. PMID: 26297827
[Ribonuclease binase induces death in T-cell acute lymphoblastic leukemia cells by apoptosis].
Burnysheva KM, Petrushanko IY, Spirin PV, Prassolov VS, Makarov AA, Mitkevich VA. Burnysheva KM, et al. Mol Biol (Mosk). 2016 Mar-Apr;50(2):347-52. doi: 10.7868/S0026898416020038. Mol Biol (Mosk). 2016. PMID: 27239856 Russian.
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