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Page 1
Publisher Correction: Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma.
Ghannam JY, Bryan J, Weiss J, Kovarsky D, Merrell D, Messer C, Schlueter-Kuck K, Fell GG, Lim-Fat MJ, Youssef G, Rahman R, Qin L, Young GS, Janes JT 3rd, Van Orden M, Pfaff KL, Gans A, Lin ES, Huang RY, Danysh BP, Parida L, Li S, Wen PY, Chiocca EA, Neuberg D, Ligon KL, Tirosh I, Reardon DA, Getz G, Wu CJ. Ghannam JY, et al. Among authors: pfaff kl. Nat Cancer. 2026 Jun 12. doi: 10.1038/s43018-026-01197-0. Online ahead of print. Nat Cancer. 2026. PMID: 42286339 No abstract available.
Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma.
Ghannam JY, Bryan J, Weiss J, Kovarsky D, Merrell D, Messer C, Schlueter-Kuck K, Fell GG, Lim-Fat MJ, Youssef G, Rahman R, Qin L, Young GS, Janes JT 3rd, Van Orden M, Pfaff KL, Gans A, Lin ES, Huang RY, Danysh BP, Parida L, Li S, Wen PY, Chiocca EA, Neuberg D, Ligon KL, Tirosh I, Reardon DA, Getz G, Wu CJ. Ghannam JY, et al. Among authors: pfaff kl. Nat Cancer. 2026 Jun 3. doi: 10.1038/s43018-026-01179-2. Online ahead of print. Nat Cancer. 2026. PMID: 42237038
Mirvetuximab soravtansine plus pembrolizumab in recurrent folate receptor alpha-positive uterine serous carcinoma: a phase II trial.
Porter RL, Zhou Y, Eskndir N, Hayes M, Polak M, Lee EK, Krasner C, Campos S, Wright AA, Liu JF, Stover EH, Sawyer H, Xiong N, Pfaff KL, Rodig SJ, Tayob N, Zweizig S, John V, Veneris J, Matulonis UA, Konstantinopoulos PA. Porter RL, et al. Among authors: pfaff kl. Nat Commun. 2026 Mar 26;17(1):4449. doi: 10.1038/s41467-026-71102-x. Nat Commun. 2026. PMID: 41888141 Free PMC article. Clinical Trial.
CRATER tumor niches facilitate CD8+ T cell engagement and correspond with immunotherapy success.
Ludin A, Stirtz GL, Tal A, Nirmal AJ, Pfaff KL, Manos M, Besson N, Eskndir N, Porter B, Jones SM, Faulkner HM, Gong Q, Liu S, Barrera I, Wu L, Pessoa Rodrigues C, Sahu A, Jerison E, Alessi JV, Ricciuti B, Richardson DS, Weiss JD, Moreau HM, Stanhope ME, Afeyan AB, Sefton J, McCall WD, Formato E, Yang S, Zhou Y, Hoytema van Konijnenburg DP, Cole HL, Cordova M, Deng L, Rajadhyaksha M, Quake SR, Awad MM, Chen F, Wucherpfennig KW, Sorger PK, Hodi FS, Rodig SJ, Murphy GF, Zon LI. Ludin A, et al. Among authors: pfaff kl. Cell. 2025 Nov 26;188(24):6720-6736.e26. doi: 10.1016/j.cell.2025.09.021. Epub 2025 Oct 17. Cell. 2025. PMID: 41109214 Free PMC article.
A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma.
Blass E, Keskin DB, Tu CR, Forman C, Vanasse A, Sax HE, Shim B, Chea V, Kim N, Carulli I, Southard J, Lyu H, Lu W, Rickles-Young M, Afeyan AB, Olive O, Mehndiratta A, Greenslade H, Shetty K, Baginska J, Gomez Diaz I, Nau A, Pfaff KL, Gans A, Ranasinghe S, Buchbinder EI, Sussman TA, Insco ML, Yoon CH, Rodig SJ, Shukla SA, Li S, Aster JC, Braun DA, Cibulskis C, Hacohen N, Neuberg DS, Giobbie-Hurder A, Livak KJ, Fritsch EF, Oliveira G, Simon JM, Wu CJ, Ott PA. Blass E, et al. Among authors: pfaff kl. Cell. 2025 Sep 18;188(19):5125-5141.e27. doi: 10.1016/j.cell.2025.06.019. Epub 2025 Jul 10. Cell. 2025. PMID: 40645179 Clinical Trial.
Phase 2, two-stage study of avelumab and axitinib in patients with mismatch repair proficient recurrent or persistent endometrial cancer.
Lee EK, Xiong N, Krasner C, Polak M, Campos S, Wright AA, Liu JF, Shea M, Yeku O, Castro C, Porter R, Stover EH, Koppermann L, Smith J, Sawyer H, Hayes M, Zhou N, Cheng SC, Bouberhan S, Pfaff KL, Rodig SJ, Jones S, Penson RT, Moroney J, Fleming GF, Matulonis UA, Konstantinopoulos PA. Lee EK, et al. Among authors: pfaff kl. Gynecol Oncol. 2025 Jul;198:1-8. doi: 10.1016/j.ygyno.2025.05.006. Epub 2025 May 20. Gynecol Oncol. 2025. PMID: 40393272 Clinical Trial.
First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell-Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Patients with Metastatic Melanoma.
Hodi FS, Giobbie-Hurder A, Adu-Berchie K, Ranasinghe S, Lako A, Severgnini M, Thrash EM, Weirather JL, Baginska J, Manos MP, Doherty EJ, Stafford A, Daley H, Ritz J, Ott PA, Pfaff KL, Rodig SJ, Yoon CH, Dranoff G, Mooney DJ. Hodi FS, et al. Among authors: pfaff kl. Cancer Immunol Res. 2025 Jul 2;13(7):978-989. doi: 10.1158/2326-6066.CIR-24-0333. Cancer Immunol Res. 2025. PMID: 40215342 Clinical Trial.
Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features.
Klughammer J, Abravanel DL, Segerstolpe Å, Blosser TR, Goltsev Y, Cui Y, Goodwin DR, Sinha A, Ashenberg O, Slyper M, Vigneau S, Jané-Valbuena J, Alon S, Caraccio C, Chen J, Cohen O, Cullen N, DelloStritto LK, Dionne D, Files J, Frangieh A, Helvie K, Hughes ME, Inga S, Kanodia A, Lako A, MacKichan C, Mages S, Moriel N, Murray E, Napolitano S, Nguyen K, Nitzan M, Ortiz R, Patel M, Pfaff KL, Porter CBM, Rotem A, Strauss S, Strasser R, Thorner AR, Turner M, Wakiro I, Waldman J, Wu J, Gómez Tejeda Zañudo J, Zhang D, Lin NU, Tolaney SM, Winer EP, Boyden ES, Chen F, Nolan GP, Rodig SJ, Zhuang X, Rozenblatt-Rosen O, Johnson BE, Regev A, Wagle N. Klughammer J, et al. Among authors: pfaff kl. Nat Med. 2025 May;31(5):1713. doi: 10.1038/s41591-025-03665-z. Nat Med. 2025. PMID: 40155562 Free PMC article. No abstract available.
Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma.
Paczkowska J, Tang M, Wright KT, Song L, Luu K, Shanmugam V, Welsh EL, Weirather JL, Besson N, Olszewski H, Porter BA, Pfaff KL, Redd RA, Cader FZ, Mandato E, Ouyang J, Calabretta E, Bai G, Lawton LN, Armand P, Rodig SJ, Liu XS, Shipp MA. Paczkowska J, et al. Among authors: pfaff kl. Nat Commun. 2024 Dec 30;15(1):10740. doi: 10.1038/s41467-024-54512-7. Nat Commun. 2024. PMID: 39737927 Free PMC article.
45 results