Pfleger CM - Search Results

1

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis.

Harvey KF, Pfleger CM, Hariharan IK. Harvey KF, et al. Among authors: pfleger cm. Cell. 2003 Aug 22;114(4):457-67. doi: 10.1016/s0092-8674(03)00557-9. Cell. 2003. PMID: 12941274

2

Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila.

Ilanges A, Jahanshahi M, Balobin DM, Pfleger CM. Ilanges A, et al. Among authors: pfleger cm. PLoS One. 2013 Oct 21;8(10):e78880. doi: 10.1371/journal.pone.0078880. eCollection 2013. PLoS One. 2013. PMID: 24205337 Free PMC article.

3

The Power of Drosophila Genetics: The Discovery of the Hippo Pathway.

Gokhale R, Pfleger CM. Gokhale R, et al. Among authors: pfleger cm. Methods Mol Biol. 2019;1893:3-26. doi: 10.1007/978-1-4939-8910-2_1. Methods Mol Biol. 2019. PMID: 30565121 Review.

4

Mutation of the gene encoding the ubiquitin activating enzyme ubal causes tissue overgrowth in Drosophila.

Pfleger CM, Harvey KF, Yan H, Hariharan IK. Pfleger CM, et al. Fly (Austin). 2007 Mar-Apr;1(2):95-105. doi: 10.4161/fly.4285. Fly (Austin). 2007. PMID: 18820468

5

Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration.

Delalle I, Pfleger CM, Buff E, Lueras P, Hariharan IK. Delalle I, et al. Among authors: pfleger cm. Genetics. 2005 Dec;171(4):1757-65. doi: 10.1534/genetics.105.049213. Epub 2005 Sep 2. Genetics. 2005. PMID: 16143599 Free PMC article.

6

Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains hematopoietic homeostasis.

Reimels TA, Pfleger CM. Reimels TA, et al. Among authors: pfleger cm. J Cell Sci. 2015 Dec 15;128(24):4512-25. doi: 10.1242/jcs.174433. Epub 2015 Nov 13. J Cell Sci. 2015. PMID: 26567216 Free PMC article.

7

The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death.

Mills K, Daish T, Harvey KF, Pfleger CM, Hariharan IK, Kumar S. Mills K, et al. Among authors: pfleger cm. J Cell Biol. 2006 Mar 13;172(6):809-15. doi: 10.1083/jcb.200512126. J Cell Biol. 2006. PMID: 16533943 Free PMC article.

8

Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo.

Yan H, Chin ML, Horvath EA, Kane EA, Pfleger CM. Yan H, et al. Among authors: pfleger cm. J Cell Sci. 2009 May 1;122(Pt 9):1461-70. doi: 10.1242/jcs.042267. Epub 2009 Apr 14. J Cell Sci. 2009. PMID: 19366732 Free PMC article.

9

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network.

Elkholi R, Abraham-Enachescu I, Trotta AP, Rubio-Patiño C, Mohammed JN, Luna-Vargas MPA, Gelles JD, Kaminetsky JR, Serasinghe MN, Zou C, Ali S, McStay GP, Pfleger CM, Chipuk JE. Elkholi R, et al. Among authors: pfleger cm. Mol Cell. 2019 May 2;74(3):452-465.e7. doi: 10.1016/j.molcel.2019.02.012. Epub 2019 Mar 14. Mol Cell. 2019. PMID: 30879903 Free PMC article.

10

Mutation in E1, the ubiquitin activating enzyme, reduces Drosophila lifespan and results in motor impairment.

Liu HY, Pfleger CM. Liu HY, et al. Among authors: pfleger cm. PLoS One. 2013;8(1):e32835. doi: 10.1371/journal.pone.0032835. Epub 2013 Jan 29. PLoS One. 2013. PMID: 23382794 Free PMC article.

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