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Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
The in vivo comet assay: use and status in genotoxicity testing.
Brendler-Schwaab S, Hartmann A, Pfuhler S, Speit G. Brendler-Schwaab S, et al. Among authors: pfuhler s. Mutagenesis. 2005 Jul;20(4):245-54. doi: 10.1093/mutage/gei033. Epub 2005 May 17. Mutagenesis. 2005. PMID: 15899933 Review.
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P. Kirkland D, et al. Among authors: pfuhler s. Mutat Res. 2007 Mar 30;628(1):31-55. doi: 10.1016/j.mrgentox.2006.11.008. Epub 2007 Jan 13. Mutat Res. 2007. PMID: 17293159
ECVAM retrospective validation of in vitro micronucleus test (MNT).
Corvi R, Albertini S, Hartung T, Hoffmann S, Maurici D, Pfuhler S, van Benthem J, Vanparys P. Corvi R, et al. Among authors: pfuhler s. Mutagenesis. 2008 Jul;23(4):271-83. doi: 10.1093/mutage/gen010. Epub 2008 Mar 7. Mutagenesis. 2008. PMID: 18326866 Free PMC article.
Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
Pfuhler S, Kirkland D, Kasper P, Hayashi M, Vanparys P, Carmichael P, Dertinger S, Eastmond D, Elhajouji A, Krul C, Rothfuss A, Schoening G, Smith A, Speit G, Thomas C, van Benthem J, Corvi R. Pfuhler S, et al. Mutat Res. 2009 Nov-Dec;680(1-2):31-42. doi: 10.1016/j.mrgentox.2009.09.002. Epub 2009 Sep 16. Mutat Res. 2009. PMID: 19765670
Emerging approaches in predictive toxicology.
Zhang L, McHale CM, Greene N, Snyder RD, Rich IN, Aardema MJ, Roy S, Pfuhler S, Venkatactahalam S. Zhang L, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2014 Dec;55(9):679-88. doi: 10.1002/em.21885. Epub 2014 Jul 9. Environ Mol Mutagen. 2014. PMID: 25044351 Free PMC article.
79 results