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Page 1
Topical Nano and Microemulsions for Skin Delivery.
Nastiti CMRR, Ponto T, Abd E, Grice JE, Benson HAE, Roberts MS. Nastiti CMRR, et al. Pharmaceutics. 2017 Sep 21;9(4):37. doi: 10.3390/pharmaceutics9040037. Pharmaceutics. 2017. PMID: 28934172 Free PMC article. Review.
Nanosystems such as microemulsions (ME) and nanoemulsions (NE) offer considerable opportunities for targeted drug delivery to and via the skin. ...The mechanism of skin delivery across the stratum corneum and via hair follicles is …
Nanosystems such as microemulsions (ME) and nanoemulsions (NE) offer considerable opportunities for targeted drug delivery
Formulation, characterization, and clinical evaluation of microemulsion containing clotrimazole for topical delivery.
Hashem FM, Shaker DS, Ghorab MK, Nasr M, Ismail A. Hashem FM, et al. AAPS PharmSciTech. 2011 Sep;12(3):879-86. doi: 10.1208/s12249-011-9653-7. Epub 2011 Jul 2. AAPS PharmSciTech. 2011. PMID: 21725708 Free PMC article.
The objective of the present study was to formulate and evaluate microemulsion systems for topical delivery of clotrimazole (CTM). ...Microemulsion formulations achieved significantly higher skin retention for CTM over the CTM cream. ...
The objective of the present study was to formulate and evaluate microemulsion systems for topical delivery of clotrima …
Design and evaluation of adapalene microemulsion for transfollicular drug delivery through guinea pig skin.
Salimi A, Sharifmakhmalzadeh B, Amirabadi FS. Salimi A, et al. J Cosmet Dermatol. 2024 Jan;23(1):289-295. doi: 10.1111/jocd.15933. Epub 2023 Jul 18. J Cosmet Dermatol. 2024. PMID: 37462297
Adapalene has a very low rate of percutaneous absorption and is almost completely insoluble in water. To obviate this problem, microemulsion (ME) carrier is used. The study's goals were to create and characterize adapalene-loaded ME and assess the drug's tran …
Adapalene has a very low rate of percutaneous absorption and is almost completely insoluble in water. To obviate this problem, microemuls
Transdermal delivery of diclofenac using water-in-oil microemulsion: formulation and mechanistic approach of drug skin permeation.
Thakkar PJ, Madan P, Lin S. Thakkar PJ, et al. Pharm Dev Technol. 2014 May;19(3):373-84. doi: 10.3109/10837450.2013.788658. Epub 2013 May 1. Pharm Dev Technol. 2014. PMID: 23634780
The objective of the present investigation was to enhance skin permeation of diclofenac using water-in-oil microemulsion and to elucidate its skin permeation mechanism. ...Permeation of diclofenac across rat skin using side-by-side permeation ce …
The objective of the present investigation was to enhance skin permeation of diclofenac using water-in-oil microemulsion and t …
Ionic liquid-in-oil microemulsion as a potential carrier of sparingly soluble drug: characterization and cytotoxicity evaluation.
Moniruzzaman M, Tamura M, Tahara Y, Kamiya N, Goto M. Moniruzzaman M, et al. Int J Pharm. 2010 Nov 15;400(1-2):243-50. doi: 10.1016/j.ijpharm.2010.08.034. Epub 2010 Sep 9. Int J Pharm. 2010. PMID: 20813174
In an approach to overcome this limitation, ionic liquid-in-oil (IL/o) microemulsions (MEs) were employed to increase the solubility of a sparingly soluble drug to enhance its topical and transdermal delivery. ...The size and size distribution of the ME dropl …
In an approach to overcome this limitation, ionic liquid-in-oil (IL/o) microemulsions (MEs) were employed to increase the solubility …
Design, Development, and Optimization of Dexibuprofen Microemulsion Based Transdermal Reservoir Patches for Controlled Drug Delivery.
Ali FR, Shoaib MH, Yousuf RI, Ali SA, Imtiaz MS, Bashir L, Naz S. Ali FR, et al. Biomed Res Int. 2017;2017:4654958. doi: 10.1155/2017/4654958. Epub 2017 Sep 27. Biomed Res Int. 2017. PMID: 29090219 Free PMC article.
In order to develop these patches, six formulations of dexibuprofen microemulsion comprising ethyl oleate, Tween 80: PG (2 : 1), and water were prepared by simplex lattice design and characterized. ...The study demonstrates that the reservoir-type transdermal …
In order to develop these patches, six formulations of dexibuprofen microemulsion comprising ethyl oleate, Tween 80: PG (2 : 1 …
Preparation, evaluation, and NMR characterization of vinpocetine microemulsion for transdermal delivery.
Hua L, Weisan P, Jiayu L, Ying Z. Hua L, et al. Drug Dev Ind Pharm. 2004 Jul;30(6):657-66. doi: 10.1081/ddc-120039183. Drug Dev Ind Pharm. 2004. PMID: 15285339
Self-diffusion coefficients were determined by PFG-NMR in order to investigate the influence of microemulsion composition with the equal drug concentration on their transdermal delivery. Finally, the microemulsion containing 1% vinpocetine was optimize …
Self-diffusion coefficients were determined by PFG-NMR in order to investigate the influence of microemulsion composition with the eq …
Design and Development of Repaglinide Microemulsion Gel for Transdermal Delivery.
Shinde UA, Modani SH, Singh KH. Shinde UA, et al. AAPS PharmSciTech. 2018 Jan;19(1):315-325. doi: 10.1208/s12249-017-0811-4. Epub 2017 Jul 17. AAPS PharmSciTech. 2018. PMID: 28717973
The developed microemulsion-based gel was characterized for globule size, zeta potential, pH, and drug content. ...The microemulsion formulation showed 12.30-fold increase in flux as compared to drug suspension with highest enhancement ra …
The developed microemulsion-based gel was characterized for globule size, zeta potential, pH, and drug content. ...The …
Development and characterization of colloidal soft nano-carriers for transdermal delivery and bioavailability enhancement of an angiotensin II receptor blocker.
Hathout RM, Elshafeey AH. Hathout RM, et al. Eur J Pharm Biopharm. 2012 Oct;82(2):230-40. doi: 10.1016/j.ejpb.2012.07.002. Epub 2012 Jul 20. Eur J Pharm Biopharm. 2012. PMID: 22820090
Different microemulsion formulations were prepared. The microemulsions were characterized visually, with the polarizing microscope, and by photon correlation spectroscopy. ...Olmesartan medoxomil delivery from the investigated formulations
Different microemulsion formulations were prepared. The microemulsions were characterized visually, with the pol …
Development and characterization of nanostructured lipid carrier-based gels for the transdermal delivery of donepezil.
Mendes IT, Ruela ALM, Carvalho FC, Freitas JTJ, Bonfilio R, Pereira GR. Mendes IT, et al. Colloids Surf B Biointerfaces. 2019 May 1;177:274-281. doi: 10.1016/j.colsurfb.2019.02.007. Epub 2019 Feb 6. Colloids Surf B Biointerfaces. 2019. PMID: 30763792
Donepezil is one of the main compounds used in the therapy of Alzheimer's disease. Oral administration of this drug presents many drawbacks, resulting in treatment non-adherence among patients. Thus, the development of transdermal formulations for donepezil deliv
Donepezil is one of the main compounds used in the therapy of Alzheimer's disease. Oral administration of this drug presents many dra …
19 results