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Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review.
Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR. Geyer MA, et al. Psychopharmacology (Berl). 2001 Jul;156(2-3):117-54. doi: 10.1007/s002130100811. Psychopharmacology (Berl). 2001. PMID: 11549216 Review.
RATIONALE: Patients with schizophrenia exhibit deficits in an operational measure of sensorimotor gating: prepulse inhibition (PPI) of startle. ...These experimentally induced PPI deficits in rats are clearly not animal models
RATIONALE: Patients with schizophrenia exhibit deficits in an operational measure of sensorimotor gating: pre
The role of N-methyl-D-aspartate receptors and metabotropic glutamate receptor 5 in the prepulse inhibition paradigms for studying schizophrenia: pharmacology, neurodevelopment, and genetics.
Wu Z, Yang Z, Zhang M, Bao X, Han F, Li L. Wu Z, et al. Behav Pharmacol. 2018 Feb;29(1):13-27. doi: 10.1097/FBP.0000000000000352. Behav Pharmacol. 2018. PMID: 29176430 Review.
Individuals with schizophrenia show deficits in prepulse inhibition (PPI), which is an operational measurement of sensorimotor gating. In this review, we focus on pharmacological, neurodevelopmental, and genetic animal mo
Individuals with schizophrenia show deficits in prepulse inhibition (PPI), which is an operational measurement o …