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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 2
1949 1
1954 5
1955 2
1956 3
1957 5
1958 3
1959 6
1960 11
1961 9
1962 6
1963 10
1964 24
1965 30
1966 42
1967 42
1968 61
1969 63
1970 71
1971 98
1972 104
1973 115
1974 141
1975 399
1976 394
1977 408
1978 384
1979 464
1980 588
1981 683
1982 763
1983 958
1984 1107
1985 1306
1986 1400
1987 1468
1988 1669
1989 1918
1990 2202
1991 2371
1992 2569
1993 2721
1994 2938
1995 3124
1996 3311
1997 3296
1998 3342
1999 3598
2000 3961
2001 4309
2002 4691
2003 4861
2004 5358
2005 5775
2006 5816
2007 6211
2008 6538
2009 6983
2010 7787
2011 8068
2012 8511
2013 8619
2014 8685
2015 8912
2016 8846
2017 8983
2018 9042
2019 9111
2020 9118
2021 9268
2022 9083
2023 9119
2024 12825
2025 18968
2026 11611

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238,845 results

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Page 1
Pharmacogenomics of oxycodone: a narrative literature review.
Umukoro NN, Aruldhas BW, Rossos R, Pawale D, Renschler JS, Sadhasivam S. Umukoro NN, et al. Pharmacogenomics. 2021 Apr;22(5):275-290. doi: 10.2217/pgs-2020-0143. Epub 2021 Mar 17. Pharmacogenomics. 2021. PMID: 33728947 Free PMC article. Review.
The evidence for clinical effect of genetic polymorphisms on oxycodone is conflicting. There is stronger evidence linking polymorphic genetic enzymes CYP2D6 and CYP3A with therapeutic outcomes. Further, research is needed to discern all of oxycodone's metabolites and their …
The evidence for clinical effect of genetic polymorphisms on oxycodone is conflicting. There is stronger evidence linking polymorphic …
Health Benefits of Culinary Herbs and Spices.
Jiang TA. Jiang TA. J AOAC Int. 2019 Mar 1;102(2):395-411. doi: 10.5740/jaoacint.18-0418. Epub 2019 Jan 16. J AOAC Int. 2019. PMID: 30651162 Free article. Review.
It is evident that frequent consumption of spicy foods was also linked to a lower risk of death from cancer and ischemic heart and respiratory system diseases. ...
It is evident that frequent consumption of spicy foods was also linked to a lower risk of death from cancer and ischemic heart and re …
In Vivo Photopharmacology.
Hüll K, Morstein J, Trauner D. Hüll K, et al. Chem Rev. 2018 Nov 14;118(21):10710-10747. doi: 10.1021/acs.chemrev.8b00037. Epub 2018 Jul 9. Chem Rev. 2018. PMID: 29985590 Review.
Synthetic photoswitches have been known for many years, but their usefulness in biology, pharmacology, and medicine has only recently been systematically explored. Over the past decade photopharmacology has grown into a vibrant field. ...These include transmembrane protein …
Synthetic photoswitches have been known for many years, but their usefulness in biology, pharmacology, and medicine has only recently …
Pharmacogenomics of TNF inhibitors.
Jan Z, El Assadi F, Velayutham D, Mifsud B, Jithesh PV. Jan Z, et al. Front Immunol. 2025 May 21;16:1521794. doi: 10.3389/fimmu.2025.1521794. eCollection 2025. Front Immunol. 2025. PMID: 40469293 Free PMC article. Review.
The review aims to summarize the recent evidence on the pharmacokinetics, pharmacodynamics, and pharmacogenomics of TNFi with a particular focus on Human Leukocyte Antigen (HLA) variants in terms of their genetic contribution to the response to TNFi. HLA variants have been lin …
The review aims to summarize the recent evidence on the pharmacokinetics, pharmacodynamics, and pharmacogenomics of TNFi with a particular f …
Thymidylate synthase pharmacogenetics.
Marsh S. Marsh S. Invest New Drugs. 2005 Dec;23(6):533-7. doi: 10.1007/s10637-005-4021-7. Invest New Drugs. 2005. PMID: 16267625 Review.
Thymidylate synthase (TYMS) is an important target for chemotherapy drugs, such as 5-fluorouracil (5FU) and methotrexate. Over-expression of TYMS is linked to resistance to TYMS-targeted chemotherapy drugs. Currently there is no protocol for selecting cancer patients at ri …
Thymidylate synthase (TYMS) is an important target for chemotherapy drugs, such as 5-fluorouracil (5FU) and methotrexate. Over-expression of …
Pharmacogenetics of Chemotherapy-Induced Cardiotoxicity.
Chang VY, Wang JJ. Chang VY, et al. Curr Oncol Rep. 2018 Apr 30;20(7):52. doi: 10.1007/s11912-018-0696-8. Curr Oncol Rep. 2018. PMID: 29713898 Free PMC article. Review.
There have been several smaller scale candidate gene approaches and a handful of genome-wide studies linking genetic variation to susceptibility to chemotherapy-induced cardiotoxicity. Currently, pharmacogenomic testing of all childhood cancer patients with an indication f …
There have been several smaller scale candidate gene approaches and a handful of genome-wide studies linking genetic variation to sus …
The Concise Guide to PHARMACOLOGY 2025/26: Catalytic receptors.
Alexander SPH, Fabbro D, Peach CJ, Gibb AJ, Kelly E, Mathie AA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kilpatrick L, Koesling D, Kuhn M, Leitinger B, MacEwan D, Monie TP, Potter LR, Russwurm M, Schmidt HHHW, Stasch JP, Waldman SA. Alexander SPH, et al. Br J Pharmacol. 2025 Dec;182 Suppl 1(Suppl 1):S259-S306. doi: 10.1111/bph.70233. Br J Pharmacol. 2025. PMID: 41461584 Free PMC article. Review.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. ...While the Concise Guide offers a more streamlined overview, more comprehensive information, including detailed phar …
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of …
Network medicine: finding the links to personalized therapy.
Chen JY, Piquette-Miller M, Smith BP. Chen JY, et al. Clin Pharmacol Ther. 2013 Dec;94(6):613-6. doi: 10.1038/clpt.2013.195. Clin Pharmacol Ther. 2013. PMID: 24241633
Network medicine is a new approach that focuses on applying systems biology to pharmacology by "understanding the molecular system [and its perturbations] as a whole" so as to unravel the complex relationships among disease processes, genes, drugs, therapeutic indicators, …
Network medicine is a new approach that focuses on applying systems biology to pharmacology by "understanding the molecular system [a …
Pharmacokinetic-pharmacodynamic relationship.
Baggot JD. Baggot JD. Ann Rech Vet. 1990;21 Suppl 1:29S-40S. Ann Rech Vet. 1990. PMID: 2080844 Review.
The dose-effect relationship can be determined by linking pharmacokinetic drug behavior with information on pharmacodynamic activity. This requires that the quantifiable concentrations of drug (or metabolites) in the plasma (systemic circulation) are related to the concent …
The dose-effect relationship can be determined by linking pharmacokinetic drug behavior with information on pharmacodynamic activity. …
Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 1: in vitro modeling of vericiguat.
Vrenken P, Vertzoni M, Frechen S, Solodenko J, Meyer M, Muenster U, Dallmann A. Vrenken P, et al. Eur J Pharm Sci. 2025 Sep 1;212:107164. doi: 10.1016/j.ejps.2025.107164. Epub 2025 Jun 10. Eur J Pharm Sci. 2025. PMID: 40505839 Free article.
Physiologically Based Biopharmaceutics Modeling (PBBM) links in vitro solubility and dissolution kinetics of oral drugs to Physiologically Based Pharmacokinetic (PBPK) models, enabling the prediction of drug bioavailability. ...Part 1 of this series introduces a novel, ope …
Physiologically Based Biopharmaceutics Modeling (PBBM) links in vitro solubility and dissolution kinetics of oral drugs to Physiologi …
238,845 results
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