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Phenotypic associations of Crohn's disease with antibodies to flagellins A4-Fla2 and Fla-X, ASCA, p-ANCA, PAB, and NOD2 mutations in a Swiss Cohort.
Schoepfer AM, Schaffer T, Mueller S, Flogerzi B, Vassella E, Seibold-Schmid B, Seibold F. Schoepfer AM, et al. Inflamm Bowel Dis. 2009 Sep;15(9):1358-67. doi: 10.1002/ibd.20892. Inflamm Bowel Dis. 2009. PMID: 19253375 Free PMC article.
BACKGROUND: Distinct Crohn's disease (CD) phenotypes correlate with antibody reactivity to microbial antigens. ...CONCLUSIONS: Anti-flagellin antibodies and ASCA are strongly associated with complicated CD phenotypes. …
BACKGROUND: Distinct Crohn's disease (CD) phenotypes correlate with antibody reactivity to microbial anti …
Analysis of Flagellin-Specific Adaptive Immunity Reveals Links to Dysbiosis in Patients With Inflammatory Bowel Disease.
Cook L, Lisko DJ, Wong MQ, Garcia RV, Himmel ME, Seidman EG, Bressler B, Levings MK, Steiner TS. Cook L, et al. Cell Mol Gastroenterol Hepatol. 2020;9(3):485-506. doi: 10.1016/j.jcmgh.2019.11.012. Epub 2019 Nov 30. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31790809 Free PMC article.
BACKGROUND & AIMS: Bacterial flagellin is an important antigen in inflammatory bowel disease, but the role of flagellin-specific CD4(+) T cells in disease pathogenesis remains unclear. ...Evidence that the phenotype of these cells strongly c …
BACKGROUND & AIMS: Bacterial flagellin is an important antigen in inflammatory bowel disease, but the role of flagellin …
Crohn's Disease Patients Uniquely Contain Inflammatory Responses to Flagellin in a CD4 Effector Memory Subset.
Morgan NN, Duck LW, Wu J, Rujani M, Thomes PG, Elson CO, Mannon PJ. Morgan NN, et al. Inflamm Bowel Dis. 2022 Aug 5:izac146. doi: 10.1093/ibd/izac146. Online ahead of print. Inflamm Bowel Dis. 2022. PMID: 35931421
BACKGROUND: Specific microbial antigens stimulate production of antibodies indicative of the aberrant immune response in Crohn's disease (CD). ...CONCLUSIONS: These findings demonstrate a Crohn's-associated flagellin-reactiv …
BACKGROUND: Specific microbial antigens stimulate production of antibodies indicative of the aberrant immune response in Crohn …