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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.
Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, Fang G, Zhang B, Yates JR 3rd, Gage FH. Brennand K, et al. Mol Psychiatry. 2015 Mar;20(3):361-8. doi: 10.1038/mp.2014.22. Epub 2014 Apr 1. Mol Psychiatry. 2015. PMID: 24686136 Free PMC article.
Consistent with recent reports indicating that neurons differentiated in vitro from human-induced pluripotent stem cells (hiPSCs) are immature relative to those in the human brain, gene expression comparisons of our hiPSC-derived n …
Consistent with recent reports indicating that neurons differentiated in vitro from human-induced pluripotent stem c
Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells.
Lee IS, Carvalho CM, Douvaras P, Ho SM, Hartley BJ, Zuccherato LW, Ladran IG, Siegel AJ, McCarthy S, Malhotra D, Sebat J, Rapoport J, Fossati V, Lupski JR, Levy DL, Brennand KJ. Lee IS, et al. NPJ Schizophr. 2015 Jun 24;1:15019-. doi: 10.1038/npjschz.2015.19. NPJ Schizophr. 2015. PMID: 26985448 Free PMC article.
Neurodevelopmental disorders, such as autism spectrum disorders (ASD) and schizophrenia (SZ), are complex disorders with a high degree of heritability. ...Here, using human induced pluripotent stem cells (hiPSCs) derived from two i …
Neurodevelopmental disorders, such as autism spectrum disorders (ASD) and schizophrenia (SZ), are complex disorders with a high degre …
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