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Phenotyping Adverse Drug Reactions: Statin-Related Myotoxicity.
Wiley LK, Moretz JD, Denny JC, Peterson JF, Bush WS. Wiley LK, et al. AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:466-70. eCollection 2015. AMIA Jt Summits Transl Sci Proc. 2015. PMID: 26306287 Free PMC article.
It is unclear the extent to which best practices for phenotyping disease states from electronic medical records (EMRs) translate to phenotyping adverse drug events. ...We conclude that phenotype algorithms for adverse drug events s …
It is unclear the extent to which best practices for phenotyping disease states from electronic medical records (EMRs) translate to …
Effect of SLCO1B1 T521C on Statin-Related Myotoxicity With Use of Lovastatin and Atorvastatin.
Lu B, Sun L, Seraydarian M, Hoffmann TJ, Medina MW, Risch N, Iribarren C, Krauss RM, Oni-Orisan A. Lu B, et al. Clin Pharmacol Ther. 2021 Sep;110(3):733-740. doi: 10.1002/cpt.2337. Epub 2021 Jul 23. Clin Pharmacol Ther. 2021. PMID: 34114646 Free PMC article.
A total of 233 statin-induced myopathy + rhabdomyolysis cases met the criteria for inclusion and were matched to 2,342 controls. To validate the drug response phenotype, we replicated the previously established association between rs4149056 genotype and simvastatin- …
A total of 233 statin-induced myopathy + rhabdomyolysis cases met the criteria for inclusion and were matched to 2,342 controls. To validate …