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PP2A:B56epsilon is required for eye induction and eye field separation.
Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM, Yang J. Rorick AM, et al. Among authors: phiel c. Dev Biol. 2007 Feb 15;302(2):477-93. doi: 10.1016/j.ydbio.2006.10.011. Epub 2006 Oct 10. Dev Biol. 2007. PMID: 17074314
Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci.
Popkie AP, Zeidner LC, Albrecht AM, D'Ippolito A, Eckardt S, Newsom DE, Groden J, Doble BW, Aronow B, McLaughlin KJ, White P, Phiel CJ. Popkie AP, et al. Among authors: phiel cj. J Biol Chem. 2010 Dec 31;285(53):41337-47. doi: 10.1074/jbc.M110.170704. Epub 2010 Nov 3. J Biol Chem. 2010. PMID: 21047779 Free PMC article.
Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells.
Meredith GD, D'Ippolito A, Dudas M, Zeidner LC, Hostetter L, Faulds K, Arnold TH, Popkie AP, Doble BW, Marnellos G, Adams C, Wang Y, Phiel CJ. Meredith GD, et al. Among authors: phiel cj. Mol Biol Cell. 2015 Jun 1;26(11):2139-50. doi: 10.1091/mbc.E15-01-0013. Epub 2015 Apr 1. Mol Biol Cell. 2015. PMID: 25833708 Free PMC article.
Functions of B56-containing PP2As in major developmental and cancer signaling pathways.
Yang J, Phiel C. Yang J, et al. Among authors: phiel c. Life Sci. 2010 Dec 18;87(23-26):659-66. doi: 10.1016/j.lfs.2010.10.003. Epub 2010 Oct 8. Life Sci. 2010. PMID: 20934435 Free PMC article. Review.
A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity.
Buescher JL, Phiel CJ. Buescher JL, et al. J Biol Chem. 2010 Mar 12;285(11):7957-63. doi: 10.1074/jbc.M109.091603. Epub 2010 Jan 15. J Biol Chem. 2010. PMID: 20080974 Free PMC article.
Targeted disruption of glycogen synthase kinase 3A (GSK3A) in mice affects sperm motility resulting in male infertility.
Bhattacharjee R, Goswami S, Dudiki T, Popkie AP, Phiel CJ, Kline D, Vijayaraghavan S. Bhattacharjee R, et al. Among authors: phiel cj. Biol Reprod. 2015 Mar;92(3):65. doi: 10.1095/biolreprod.114.124495. Epub 2015 Jan 7. Biol Reprod. 2015. PMID: 25568307 Free PMC article.
Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells.
Faulds KJ, Egelston JN, Sedivy LJ, Mitchell MK, Garimella S, Kozlowski H, D'Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ. Faulds KJ, et al. Among authors: phiel cj. J Biol Chem. 2018 Jul 6;293(27):10731-10743. doi: 10.1074/jbc.RA117.001298. Epub 2018 May 18. J Biol Chem. 2018. PMID: 29777057 Free PMC article.
The role for oxidative stress in aberrant DNA methylation in Alzheimer's disease.
Fleming JL, Phiel CJ, Toland AE. Fleming JL, et al. Curr Alzheimer Res. 2012 Nov;9(9):1077-96. doi: 10.2174/156720512803569000. Curr Alzheimer Res. 2012. PMID: 21605062 Review.
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3.
Zhang F, Phiel CJ, Spece L, Gurvich N, Klein PS. Zhang F, et al. J Biol Chem. 2003 Aug 29;278(35):33067-77. doi: 10.1074/jbc.M212635200. Epub 2003 Jun 7. J Biol Chem. 2003. PMID: 12796505
A novel interaction between Glycogen Synthase Kinase-3α (GSK-3α) and the scaffold protein Receptor for Activated C-Kinase 1 (RACK1) regulates the circadian clock.
Zeidner LC, Buescher JL, Phiel CJ. Zeidner LC, et al. Among authors: phiel cj. Int J Biochem Mol Biol. 2011;2(4):318-27. Epub 2011 Nov 20. Int J Biochem Mol Biol. 2011. PMID: 22187666 Free PMC article.
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