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91 results

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Page 1
Effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in glial and neuronal cells of the central nervous system.
Ramesh G, Martinez AN, Martin DS, Philipp MT. Ramesh G, et al. J Neuroinflammation. 2017 Feb 2;14(1):28. doi: 10.1186/s12974-017-0806-9. J Neuroinflammation. 2017. PMID: 28153013 Free PMC article.
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), affects both the central and peripheral nervous systems. ...
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), affects both the central and peripheral …
Transcriptional regulation in spirochetes.
Indest KJ, Ramamoorthy R, Philipp MT. Indest KJ, et al. J Mol Microbiol Biotechnol. 2000 Oct;2(4):473-81. J Mol Microbiol Biotechnol. 2000. PMID: 11075920 Review.
Despite the fact that the complete genome sequence of two species, Borrelia burgdorferi and Treponema pallidum, have been deciphered, much remains to be understood about spirochetal gene regulation. ...
Despite the fact that the complete genome sequence of two species, Borrelia burgdorferi and Treponema pallidum, have been deciphered, …
Non-viable Borrelia burgdorferi induce inflammatory mediators and apoptosis in human oligodendrocytes.
Parthasarathy G, Fevrier HB, Philipp MT. Parthasarathy G, et al. Neurosci Lett. 2013 Nov 27;556:200-3. doi: 10.1016/j.neulet.2013.10.032. Epub 2013 Oct 22. Neurosci Lett. 2013. PMID: 24157855 Free PMC article.
In previous studies, exposure to live Borrelia burgdorferi was shown to induce inflammation and apoptosis of human oligodendrocytes. ...
In previous studies, exposure to live Borrelia burgdorferi was shown to induce inflammation and apoptosis of human oligodendrocytes. …
Anti-inflammatory effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in neuronal cultures of dorsal root ganglia and myelinating cells of the peripheral nervous system.
Ramesh G, Meisner OC, Philipp MT. Ramesh G, et al. J Neuroinflammation. 2015 Dec 23;12:240. doi: 10.1186/s12974-015-0461-y. J Neuroinflammation. 2015. PMID: 26700298 Free PMC article.
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), could result in cognitive impairment, motor dysfunction, and radiculoneuritis. ...
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), could result in cognitive impairment, mo …
The Lyme disease spirochete Borrelia burgdorferi induces inflammation and apoptosis in cells from dorsal root ganglia.
Ramesh G, Santana-Gould L, Inglis FM, England JD, Philipp MT. Ramesh G, et al. J Neuroinflammation. 2013 Jul 18;10:88. doi: 10.1186/1742-2094-10-88. J Neuroinflammation. 2013. PMID: 23866773 Free PMC article.
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi, affects both the peripheral and the central nervous systems. ...
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi, affects both the peripheral and the central n …
Phosphoenolpyruvate Phosphotransferase System Components Modulate Gene Transcription and Virulence of Borrelia burgdorferi.
Khajanchi BK, Odeh E, Gao L, Jacobs MB, Philipp MT, Lin T, Norris SJ. Khajanchi BK, et al. Infect Immun. 2015 Dec 28;84(3):754-64. doi: 10.1128/IAI.00917-15. Infect Immun. 2015. PMID: 26712207 Free PMC article.
The phosphoenolpyruvate phosphotransferase system (PEP-PTS) and adenylate cyclase (AC) IV (encoded by BB0723 [cyaB]) are well conserved in different species of Borrelia. However, the functional roles of PEP-PTS and AC in the infectious cycle of Borrelia have not bee …
The phosphoenolpyruvate phosphotransferase system (PEP-PTS) and adenylate cyclase (AC) IV (encoded by BB0723 [cyaB]) are well conserved in d …
Induction of pro- and anti-inflammatory cytokines by Borrelia burgdorferi lipoproteins in monocytes is mediated by CD14.
Giambartolomei GH, Dennis VA, Lasater BL, Philipp MT. Giambartolomei GH, et al. Infect Immun. 1999 Jan;67(1):140-7. doi: 10.1128/IAI.67.1.140-147.1999. Infect Immun. 1999. PMID: 9864208 Free PMC article.
We previously showed that heat-killed Borrelia burgdorferi spirochetes and lipidated outer surface protein A (L-OspA) stimulated the in vitro production of interleukin-10 (IL-10) in peripheral blood mononuclear cells (PBMC) from uninfected humans and rhesus monkeys (G. ...
We previously showed that heat-killed Borrelia burgdorferi spirochetes and lipidated outer surface protein A (L-OspA) stimulated the …
Dynamic longitudinal antibody responses during Borrelia burgdorferi infection and antibiotic treatment of rhesus macaques.
Embers ME, Hasenkampf NR, Jacobs MB, Philipp MT. Embers ME, et al. Clin Vaccine Immunol. 2012 Aug;19(8):1218-26. doi: 10.1128/CVI.00228-12. Epub 2012 Jun 20. Clin Vaccine Immunol. 2012. PMID: 22718128 Free PMC article.
Infection with Borrelia burgdorferi elicits robust yet disparate antibody responses in infected individuals. ...
Infection with Borrelia burgdorferi elicits robust yet disparate antibody responses in infected individuals. ...
Lyme neuroborreliosis in the rhesus monkey.
England JD, Bohm RP Jr, Roberts ED, Philipp MT. England JD, et al. Semin Neurol. 1997 Mar;17(1):53-6. doi: 10.1055/s-2008-1040913. Semin Neurol. 1997. PMID: 9166960 Review.
Although there are several animal models of Lyme disease, only the rhesus monkey model exhibits all of the key manifestations of the disease. After infection with Borrelia burgdorferi, rhesus monkeys develop signs of early localized, early disseminated, and chronic Lyme di …
Although there are several animal models of Lyme disease, only the rhesus monkey model exhibits all of the key manifestations of the disease …
Analysis of Borrelia burgdorferi vlsE gene expression and recombination in the tick vector.
Indest KJ, Howell JK, Jacobs MB, Scholl-Meeker D, Norris SJ, Philipp MT. Indest KJ, et al. Infect Immun. 2001 Nov;69(11):7083-90. doi: 10.1128/IAI.69.11.7083-7090.2001. Infect Immun. 2001. PMID: 11598084 Free PMC article.
Expression and recombination of the antigenic variation vlsE gene of the Lyme disease spirochete Borrelia burgdorferi were analyzed in the tick vector. To assess vlsE expression, Ixodes scapularis nymphs infected with the B. burgdorferi strain B31 were fed on mice for 48 o …
Expression and recombination of the antigenic variation vlsE gene of the Lyme disease spirochete Borrelia burgdorferi were analyzed i …
91 results