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1993 1
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1997 4
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2000 8
2001 6
2002 3
2003 7
2004 3
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2006 4
2007 3
2008 4
2009 5
2011 1
2012 5
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2014 1
2015 5
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2017 4
2018 1
2019 1
2021 0
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Page 1
Effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in glial and neuronal cells of the central nervous system.
Ramesh G, Martinez AN, Martin DS, Philipp MT. Ramesh G, et al. J Neuroinflammation. 2017 Feb 2;14(1):28. doi: 10.1186/s12974-017-0806-9. J Neuroinflammation. 2017. PMID: 28153013 Free PMC article.
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), affects both the central and peripheral nervous systems. ...
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), affects both the central and peripheral …
Anti-inflammatory effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in neuronal cultures of dorsal root ganglia and myelinating cells of the peripheral nervous system.
Ramesh G, Meisner OC, Philipp MT. Ramesh G, et al. J Neuroinflammation. 2015 Dec 23;12:240. doi: 10.1186/s12974-015-0461-y. J Neuroinflammation. 2015. PMID: 26700298 Free PMC article.
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), could result in cognitive impairment, motor dysfunction, and radiculoneuritis. ...
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), could result in cognitive impairment, mo …
The Lyme disease spirochete Borrelia burgdorferi induces inflammation and apoptosis in cells from dorsal root ganglia.
Ramesh G, Santana-Gould L, Inglis FM, England JD, Philipp MT. Ramesh G, et al. J Neuroinflammation. 2013 Jul 18;10:88. doi: 10.1186/1742-2094-10-88. J Neuroinflammation. 2013. PMID: 23866773 Free PMC article.
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi, affects both the peripheral and the central nervous systems. ...
BACKGROUND: Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi, affects both the peripheral and the central n …
Non-viable Borrelia burgdorferi induce inflammatory mediators and apoptosis in human oligodendrocytes.
Parthasarathy G, Fevrier HB, Philipp MT. Parthasarathy G, et al. Neurosci Lett. 2013 Nov 27;556:200-3. doi: 10.1016/j.neulet.2013.10.032. Epub 2013 Oct 22. Neurosci Lett. 2013. PMID: 24157855 Free PMC article.
In previous studies, exposure to live Borrelia burgdorferi was shown to induce inflammation and apoptosis of human oligodendrocytes. ...
In previous studies, exposure to live Borrelia burgdorferi was shown to induce inflammation and apoptosis of human oligodendrocytes. …
Phosphoenolpyruvate Phosphotransferase System Components Modulate Gene Transcription and Virulence of Borrelia burgdorferi.
Khajanchi BK, Odeh E, Gao L, Jacobs MB, Philipp MT, Lin T, Norris SJ. Khajanchi BK, et al. Infect Immun. 2015 Dec 28;84(3):754-64. doi: 10.1128/IAI.00917-15. Infect Immun. 2015. PMID: 26712207 Free PMC article.
The phosphoenolpyruvate phosphotransferase system (PEP-PTS) and adenylate cyclase (AC) IV (encoded by BB0723 [cyaB]) are well conserved in different species of Borrelia. However, the functional roles of PEP-PTS and AC in the infectious cycle of Borrelia have not bee …
The phosphoenolpyruvate phosphotransferase system (PEP-PTS) and adenylate cyclase (AC) IV (encoded by BB0723 [cyaB]) are well conserved in d …
Dynamic longitudinal antibody responses during Borrelia burgdorferi infection and antibiotic treatment of rhesus macaques.
Embers ME, Hasenkampf NR, Jacobs MB, Philipp MT. Embers ME, et al. Clin Vaccine Immunol. 2012 Aug;19(8):1218-26. doi: 10.1128/CVI.00228-12. Epub 2012 Jun 20. Clin Vaccine Immunol. 2012. PMID: 22718128 Free PMC article.
Infection with Borrelia burgdorferi elicits robust yet disparate antibody responses in infected individuals. ...
Infection with Borrelia burgdorferi elicits robust yet disparate antibody responses in infected individuals. ...
The MEK/ERK pathway is the primary conduit for Borrelia burgdorferi-induced inflammation and P53-mediated apoptosis in oligodendrocytes.
Parthasarathy G, Philipp MT. Parthasarathy G, et al. Apoptosis. 2014 Jan;19(1):76-89. doi: 10.1007/s10495-013-0913-8. Apoptosis. 2014. PMID: 24114360 Free PMC article.
In a rhesus macaque model of LNB we had previously shown that brains of rhesus macaques inoculated with Borrelia burgdorferi release inflammatory mediators, and undergo oligodendrocyte and neuronal cell death. ...
In a rhesus macaque model of LNB we had previously shown that brains of rhesus macaques inoculated with Borrelia burgdorferi release …
Variable manifestations, diverse seroreactivity and post-treatment persistence in non-human primates exposed to Borrelia burgdorferi by tick feeding.
Embers ME, Hasenkampf NR, Jacobs MB, Tardo AC, Doyle-Meyers LA, Philipp MT, Hodzic E. Embers ME, et al. PLoS One. 2017 Dec 13;12(12):e0189071. doi: 10.1371/journal.pone.0189071. eCollection 2017. PLoS One. 2017. PMID: 29236732 Free PMC article.
While experimental studies in animals have offered evidence of post-treatment persistence of Borrelia burgdorferi, variations in methodology, detection methods and limitations of the models have led to some uncertainty with respect to translation of these results to human …
While experimental studies in animals have offered evidence of post-treatment persistence of Borrelia burgdorferi, variations in meth …
Central role of the Holliday junction helicase RuvAB in vlsE recombination and infectivity of Borrelia burgdorferi.
Lin T, Gao L, Edmondson DG, Jacobs MB, Philipp MT, Norris SJ. Lin T, et al. PLoS Pathog. 2009 Dec;5(12):e1000679. doi: 10.1371/journal.ppat.1000679. Epub 2009 Dec 4. PLoS Pathog. 2009. PMID: 19997622 Free PMC article.
Antigenic variation plays a vital role in the pathogenesis of many infectious bacteria and protozoa including Borrelia burgdorferi, the causative agent of Lyme disease. VlsE, a 35 kDa surface-exposed lipoprotein, undergoes antigenic variation during B. burgdorferi infectio …
Antigenic variation plays a vital role in the pathogenesis of many infectious bacteria and protozoa including Borrelia burgdorferi, t …
Induction of pro- and anti-inflammatory cytokines by Borrelia burgdorferi lipoproteins in monocytes is mediated by CD14.
Giambartolomei GH, Dennis VA, Lasater BL, Philipp MT. Giambartolomei GH, et al. Infect Immun. 1999 Jan;67(1):140-7. doi: 10.1128/IAI.67.1.140-147.1999. Infect Immun. 1999. PMID: 9864208 Free PMC article.
We previously showed that heat-killed Borrelia burgdorferi spirochetes and lipidated outer surface protein A (L-OspA) stimulated the in vitro production of interleukin-10 (IL-10) in peripheral blood mononuclear cells (PBMC) from uninfected humans and rhesus monkeys (G. ...
We previously showed that heat-killed Borrelia burgdorferi spirochetes and lipidated outer surface protein A (L-OspA) stimulated the …
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