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PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.
Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB. Hughes SK, et al. Among authors: philippar u. Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2. Mol Biol Cell. 2015. PMID: 26337385 Free PMC article.
Filopodia are required for cortical neurite initiation.
Dent EW, Kwiatkowski AV, Mebane LM, Philippar U, Barzik M, Rubinson DA, Gupton S, Van Veen JE, Furman C, Zhang J, Alberts AS, Mori S, Gertler FB. Dent EW, et al. Among authors: philippar u. Nat Cell Biol. 2007 Dec;9(12):1347-59. doi: 10.1038/ncb1654. Epub 2007 Nov 18. Nat Cell Biol. 2007. PMID: 18026093
Ena/VASP Is Required for neuritogenesis in the developing cortex.
Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fässler R, Gertler FB. Kwiatkowski AV, et al. Among authors: philippar u. Neuron. 2007 Nov 8;56(3):441-55. doi: 10.1016/j.neuron.2007.09.008. Neuron. 2007. PMID: 17988629 Free article.
Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines.
Pino MS, Balsamo M, Di Modugno F, Mottolese M, Alessio M, Melucci E, Milella M, McConkey DJ, Philippar U, Gertler FB, Natali PG, Nisticò P. Pino MS, et al. Among authors: philippar u. Clin Cancer Res. 2008 Aug 1;14(15):4943-50. doi: 10.1158/1078-0432.CCR-08-0436. Clin Cancer Res. 2008. PMID: 18676769 Free PMC article.
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.
Philippar U, Schratt G, Dieterich C, Müller JM, Galgóczy P, Engel FB, Keating MT, Gertler F, Schüle R, Vingron M, Nordheim A. Philippar U, et al. Mol Cell. 2004 Dec 22;16(6):867-80. doi: 10.1016/j.molcel.2004.11.039. Mol Cell. 2004. PMID: 15610731 Free article.
Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation.
Zhang J, Fu L, Shen B, Liu Y, Wang W, Cai X, Kong L, Yan Y, Meng R, Zhang Z, Chen YP, Liu Q, Wan ZK, Zhou T, Wang X, Gavine P, Del Rosario A, Ahn K, Philippar U, Attar R, Yang J, Xu Y, Edwards JP, Dai X. Zhang J, et al. Among authors: philippar u. Cell Chem Biol. 2020 Dec 17;27(12):1500-1509.e13. doi: 10.1016/j.chembiol.2020.08.010. Epub 2020 Sep 3. Cell Chem Biol. 2020. PMID: 32888499 Free article.
28 results