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Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.
Jarlier V, Nicolas MH, Fournier G, Philippon A. Jarlier V, et al. Rev Infect Dis. 1988 Jul-Aug;10(4):867-78. doi: 10.1093/clinids/10.4.867. Rev Infect Dis. 1988. PMID: 3263690
The enzymes conferred to derivatives a high level of resistance to amoxicillin, ticarcillin, piperacillin, and cephalothin and a decreased degree of susceptibility (i.e., MICs increased by 10- to 800-fold) to cefotaxime, ceftriaxone, ceftazidime, and aztreonam. ... …
The enzymes conferred to derivatives a high level of resistance to amoxicillin, ticarcillin, piperacillin, and cephalothin and a
[Extended spectrum beta-lactamases].
Philippon A, Arlet G, Lagrange P. Philippon A, et al. Rev Prat. 1993 Nov 15;43(18):2387-95. Rev Prat. 1993. PMID: 8128161 Review. French.
A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, blood, wound, sputum cultures) mostly recovered from patients in intensive care units. ...Treatment including a beta-lactam is still possible because of the stability of some
A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, blood, wound, sputum cultures) mostly rec
[Comparative effect of beta-lactam activity on Pseudomonas aeruginosa as a function of resistance phenotypes].
Thabaut A, Philippon A, Meyran M. Thabaut A, et al. Presse Med. 1984 Mar 29;13(13):768-71. Presse Med. 1984. PMID: 6231592 French.
In a multicentre study of the distribution in France of constitutive beta-lactamases produced by Ps. aeruginosa, the activities of 12 antibiotics were investigated comparatively according to resistance phenotypes. Antibiotics with the best activity, on a weight-for- …
In a multicentre study of the distribution in France of constitutive beta-lactamases produced by Ps. aeruginosa, the activities of 12 …
[Antibacterial effect of cefixime in the presence of the type of beta-lactamases produced by Enterobacteriaceae].
Philippon A, Jarlier V, Legrand P, Fournier G, Nicolas MH, Duval J. Philippon A, et al. Presse Med. 1989 Oct 11;18(32):1560-6. Presse Med. 1989. PMID: 2530532 French.
Sixty-one derivatives were constructed producing TEM-1, TEM-2, SHV-1, CTX-1, TEM-4, CAZ-2, SHV-2, SHV-3, SHV-4, the MICs of cefixime were stable against derivatives producing a penicillinase (TEM-1, TEM-2, SHV-1), but not against those producing an ESB. ...
Sixty-one derivatives were constructed producing TEM-1, TEM-2, SHV-1, CTX-1, TEM-4, CAZ-2, SHV-2, SHV-3, SHV-4, the MICs of cefixime were st …
Oligonucleotide probes (TEM-1, OXA-1) versus isoelectric focusing in beta-lactamase characterization of 114 resistant strains.
Ouellette M, Paul GC, Philippon AM, Roy PH. Ouellette M, et al. Antimicrob Agents Chemother. 1988 Mar;32(3):397-9. doi: 10.1128/aac.32.3.397. Antimicrob Agents Chemother. 1988. PMID: 3259123 Free PMC article.
TEM-4, a new plasmid-mediated beta-lactamase that hydrolyzes broad-spectrum cephalosporins in a clinical isolate of Escherichia coli.
Paul GC, Gerbaud G, Bure A, Philippon AM, Pangon B, Courvalin P. Paul GC, et al. Antimicrob Agents Chemother. 1989 Nov;33(11):1958-63. doi: 10.1128/aac.33.11.1958. Antimicrob Agents Chemother. 1989. PMID: 2692515 Free PMC article.
A beta-lactamase with an isoelectric point (pI) of 5.9 was detected in strain CB-134, and the corresponding gene was transferred by conjugation to E. coli together with the associated aminoglycoside resistance determinant [AAC(3)-II] and tetracycline, trimethoprim, and sul
A beta-lactamase with an isoelectric point (pI) of 5.9 was detected in strain CB-134, and the corresponding gene was transferred by c
In vitro susceptibilities of 126 clinical isolates of Yersinia enterocolitica to 21 beta-lactam antibiotics.
Hornstein MJ, Jupeau AM, Scavizzi MR, Philippon AM, Grimont PA. Hornstein MJ, et al. Antimicrob Agents Chemother. 1985 May;27(5):806-11. doi: 10.1128/aac.27.5.806. Antimicrob Agents Chemother. 1985. PMID: 2990327 Free PMC article.
A principal component analysis of MIC data separated the major serotypes (O3, O9, O8, and O5,27). The MCBs of 14 newer beta-lactams were measured against 10 clinical isolates. On the basis of the ratio of MBC to MIC (expressed in dilution factors), a real bactericid
A principal component analysis of MIC data separated the major serotypes (O3, O9, O8, and O5,27). The MCBs of 14 newer beta-lactams w
[Beta-lactamases of ampicillin-resistant Salmonella].
Philippon A, Fournier G, Cornel E, Paul G, Le Minor L, Nevot P. Philippon A, et al. Ann Microbiol (Paris). 1984 Mar-Apr;135A(2):229-38. Ann Microbiol (Paris). 1984. PMID: 6609659 French.
[Distribution of constituent beta-lactamases in Pseudomonas aeruginosa].
Philippon A, Thabaut A, Meyran M, Nevot P. Philippon A, et al. Presse Med. 1984 Mar 29;13(13):772-6. Presse Med. 1984. PMID: 6231593 French.
With beta-lactam antibiotics (cefotaxime, moxalactam, ceftazidime) that resist hydrolysis, bacterial resistance is due to production of a constitutive beta-lactamase of the cephalosporinase type. ...
With beta-lactam antibiotics (cefotaxime, moxalactam, ceftazidime) that resist hydrolysis, bacterial resistance is due to production of a
Susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics.
Philippon A. Philippon A. Chemioterapia. 1985 Dec;4(6):424-8. Chemioterapia. 1985. PMID: 3938346
A few surveys on the resistance mechanism indicated that impermeability can be prevalent, instead beta-lactamases. But in any case, the enzyme distribution showed carbenicillinases (PSE-1, PSE-4) and OXA were observed with a high prevalence among ticarcillin-resista
A few surveys on the resistance mechanism indicated that impermeability can be prevalent, instead beta-lactamases. But in any case, t
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