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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1979 1
1982 2
1983 2
1985 3
1986 4
1987 2
1988 2
1989 1
1990 1
1991 2
1992 3
1993 4
1994 3
1995 2
1996 4
1997 3
1998 5
1999 5
2000 5
2001 4
2002 7
2003 4
2004 7
2005 7
2006 7
2007 6
2008 12
2009 9
2010 7
2011 6
2012 7
2013 15
2014 10
2015 9
2016 8
2017 9
2018 12
2019 14
2020 5
2021 6
2022 4
2023 5

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216 results

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Page 1
Ulcerative colitis.
Le Berre C, Honap S, Peyrin-Biroulet L. Le Berre C, et al. Lancet. 2023 Aug 12;402(10401):571-584. doi: 10.1016/S0140-6736(23)00966-2. Lancet. 2023. PMID: 37573077 Review.
Ulcerative colitis is thought to occur in people with a genetic predisposition following environmental exposures; gut epithelial barrier defects, the microbiota, and a dysregulated immune response are strongly implicated. ...Maintenance treatments include 5-aminosalicylic …
Ulcerative colitis is thought to occur in people with a genetic predisposition following environmental exposures; gut epithelial barrier …
Regulation of Clathrin-Mediated Endocytosis.
Mettlen M, Chen PH, Srinivasan S, Danuser G, Schmid SL. Mettlen M, et al. Annu Rev Biochem. 2018 Jun 20;87:871-896. doi: 10.1146/annurev-biochem-062917-012644. Epub 2018 Apr 16. Annu Rev Biochem. 2018. PMID: 29661000 Free PMC article. Review.
It is responsible for the uptake of transmembrane receptors and transporters, for remodeling plasma membrane composition in response to environmental changes, and for regulating cell surface signaling. CME occurs via the assembly and maturation of clathrin-coated pi …
It is responsible for the uptake of transmembrane receptors and transporters, for remodeling plasma membrane composition in re …
Urinary pH and stone formation.
Wagner CA, Mohebbi N. Wagner CA, et al. J Nephrol. 2010 Nov-Dec;23 Suppl 16:S165-9. J Nephrol. 2010. PMID: 21170875 Free article. Review.
The activity of many transport processes involved in calcium, citrate and phosphate handling are sensitive to changes in systemic or local pH as shown for several phosphate transporters, the citrate transporter NaDC1 and the TRPV5 calcium channe …
The activity of many transport processes involved in calcium, citrate and phosphate handling are sensitive to changes in syste …
Glucose, glycolysis, and neurodegenerative diseases.
Tang BL. Tang BL. J Cell Physiol. 2020 Nov;235(11):7653-7662. doi: 10.1002/jcp.29682. Epub 2020 Apr 2. J Cell Physiol. 2020. PMID: 32239718 Review.
Prolonged survival of a typical postmitotic neuron hinges on a balance between multiple processes, among these are a sustenance of ATP production and protection against reactive oxygen species. In neuropathological conditions, mitochondrial defects often lead to both a dro …
Prolonged survival of a typical postmitotic neuron hinges on a balance between multiple processes, among these are a sustenance of ATP produ …
Immunometabolism in the development of rheumatoid arthritis.
Weyand CM, Goronzy JJ. Weyand CM, et al. Immunol Rev. 2020 Mar;294(1):177-187. doi: 10.1111/imr.12838. Epub 2020 Jan 27. Immunol Rev. 2020. PMID: 31984519 Free PMC article. Review.
A typifying property of RA CD4 T cells is the shunting of glucose away from glycolytic breakdown and mitochondrial processing toward the pentose phosphate pathway, favoring anabolic over catabolic reactions. Key defects have been localized to the mitochondria and th …
A typifying property of RA CD4 T cells is the shunting of glucose away from glycolytic breakdown and mitochondrial processing toward the pen …
Getting out what you put in: Copper in mitochondria and its impacts on human disease.
Cobine PA, Moore SA, Leary SC. Cobine PA, et al. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118867. doi: 10.1016/j.bbamcr.2020.118867. Epub 2020 Oct 2. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 32979421 Free PMC article. Review.
Mitochondria accumulate copper in their matrix for the eventual maturation of the cuproenzymes cytochrome c oxidase and superoxide dismutase. Transport into the matrix is achieved by mitochondrial carrier family (MCF) proteins. ...The Pic2 ortholog SLC25A3, one of 5 …
Mitochondria accumulate copper in their matrix for the eventual maturation of the cuproenzymes cytochrome c oxidase and superoxide dismutase …
Potential role and therapeutic interests of myo-inositol in metabolic diseases.
Croze ML, Soulage CO. Croze ML, et al. Biochimie. 2013 Oct;95(10):1811-27. doi: 10.1016/j.biochi.2013.05.011. Epub 2013 Jun 10. Biochimie. 2013. PMID: 23764390 Review.
Several inositol isomers and in particular myo-inositol (MI) and D-chiro-inositol (DCI), were shown to possess insulin-mimetic properties and to be efficient in lowering post-prandial blood glucose. In addition, abnormalities in inositol metabolism are associated with insu …
Several inositol isomers and in particular myo-inositol (MI) and D-chiro-inositol (DCI), were shown to possess insulin-mimetic properties an …
Phosphate homeostasis disorders.
Christov M, Jüppner H. Christov M, et al. Best Pract Res Clin Endocrinol Metab. 2018 Oct;32(5):685-706. doi: 10.1016/j.beem.2018.06.004. Epub 2018 Jun 18. Best Pract Res Clin Endocrinol Metab. 2018. PMID: 30449549 Review.
Our understanding of the regulation of phosphate balance has benefited tremendously from the molecular identification and characterization of genetic defects leading to a number of rare inherited or acquired disorders affecting phosphate homeostasis. The iden …
Our understanding of the regulation of phosphate balance has benefited tremendously from the molecular identification and characteriz …
Urea cycle disorders-update.
Matsumoto S, Häberle J, Kido J, Mitsubuchi H, Endo F, Nakamura K. Matsumoto S, et al. J Hum Genet. 2019 Sep;64(9):833-847. doi: 10.1038/s10038-019-0614-4. Epub 2019 May 20. J Hum Genet. 2019. PMID: 31110235 Review.
The urea cycle disorders (UCDs) comprise diseases presenting with hyperammonemia that arise in either the neonatal period (about 50% of cases) or later. Congenital defects of the enzymes or transporters of the urea cycle cause the disease. This cycle utilizes five e …
The urea cycle disorders (UCDs) comprise diseases presenting with hyperammonemia that arise in either the neonatal period (about 50% of case …
Renal phosphate handling and inherited disorders of phosphate reabsorption: an update.
Wagner CA, Rubio-Aliaga I, Hernando N. Wagner CA, et al. Pediatr Nephrol. 2019 Apr;34(4):549-559. doi: 10.1007/s00467-017-3873-3. Epub 2017 Dec 23. Pediatr Nephrol. 2019. PMID: 29275531 Free article. Review.
Renal phosphate handling critically determines plasma phosphate and whole body phosphate levels. Filtered phosphate is mostly reabsorbed by Na(+)-dependent phosphate transporters located in the brush border membrane of the proximal …
Renal phosphate handling critically determines plasma phosphate and whole body phosphate levels. Filtered phosphate
216 results