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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 2
1959 1
1962 1
1963 3
1964 3
1965 6
1966 2
1967 6
1968 4
1969 9
1970 3
1971 6
1972 9
1973 9
1974 18
1975 41
1976 33
1977 67
1978 43
1979 37
1980 36
1981 24
1982 40
1983 27
1984 45
1985 35
1986 38
1987 29
1988 26
1989 39
1990 22
1991 26
1992 17
1993 22
1994 15
1995 21
1996 21
1997 20
1998 22
1999 26
2000 13
2001 13
2002 17
2003 22
2004 18
2005 16
2006 15
2007 12
2008 12
2009 9
2010 15
2011 16
2012 17
2013 18
2014 18
2015 19
2016 16
2017 20
2018 32
2019 24
2020 32
2021 34
2022 20
2023 1
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1,231 results
Results by year
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Page 1
Human de novo purine biosynthesis.
Pareek V, Pedley AM, Benkovic SJ. Pareek V, et al. Crit Rev Biochem Mol Biol. 2021 Feb;56(1):1-16. doi: 10.1080/10409238.2020.1832438. Epub 2020 Nov 12. Crit Rev Biochem Mol Biol. 2021. PMID: 33179964 Free PMC article. Review.
The finding that fluorescently-tagged chimeras of the pathway enzymes form discrete puncta, now called purinosomes, is further elaborated in this review to include: a discussion of their assembly; the role of ancillary proteins; their locus at the microtubule/mitochondria interfa …
The finding that fluorescently-tagged chimeras of the pathway enzymes form discrete puncta, now called purinosomes, is further elaborated in …
Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair.
Liu R, Li J, Shao J, Lee JH, Qiu X, Xiao Y, Zhang B, Hao Y, Li M, Chen Q. Liu R, et al. Cell Metab. 2021 Oct 5;33(10):2076-2089.e9. doi: 10.1016/j.cmet.2021.07.009. Epub 2021 Aug 2. Cell Metab. 2021. PMID: 34343500 Free article.
Here, we show that ionizing radiation results in TBK1-mediated phosphorylation of phosphoribosyl pyrophosphate synthetase (PRPS)1/2 at T228, thereby enhancing PRPS1/2 catalytic activity and promoting deoxyribonucleotide synthesis. ...
Here, we show that ionizing radiation results in TBK1-mediated phosphorylation of phosphoribosyl pyrophosphate synthetase (PRP …
Experimental Clarification of PRPS-1 Structural Essentials.
Danielyan KE, Grabski HV, Ginosyan SV, Chailyan SG, Tiratsuyan SG. Danielyan KE, et al. Cell Biochem Biophys. 2022 Dec;80(4):699-709. doi: 10.1007/s12013-022-01104-1. Epub 2022 Oct 6. Cell Biochem Biophys. 2022. PMID: 36201097
Phosphoribosyl pyrophosphate synthetase-1 (PRPS-1; EC 2.7.6.1.) catalyzes the binding of phosphate-group to ribose 5-phosphate, forming the 5-phosphoribosyl-1-pyrophosphate, which is necessary for the salvage pathways of purine and pyrimidine, pyridine
Phosphoribosyl pyrophosphate synthetase-1 (PRPS-1; EC 2.7.6.1.) catalyzes the binding of phosphate-group to ribose 5-phosphate
Filamentation modulates allosteric regulation of PRPS.
Hu HH, Lu GM, Chang CC, Li Y, Zhong J, Guo CJ, Zhou X, Yin B, Zhang T, Liu JL. Hu HH, et al. Elife. 2022 Jun 23;11:e79552. doi: 10.7554/eLife.79552. Elife. 2022. PMID: 35736577 Free PMC article.
Phosphoribosyl pyrophosphate (PRPP) is a key intermediate in the biosynthesis of purine and pyrimidine nucleotides, histidine, tryptophan, and cofactors NAD and NADP. ...
Phosphoribosyl pyrophosphate (PRPP) is a key intermediate in the biosynthesis of purine and pyrimidine nucleotides, histidine,
Amidophosphoribosyltransferase.
Zalkin H. Zalkin H. Methods Enzymol. 1985;113:264-73. doi: 10.1016/s0076-6879(85)13036-3. Methods Enzymol. 1985. PMID: 2418333 No abstract available.
Mechanosensitive turnover of phosphoribosyl pyrophosphate synthetases regulates nucleotide metabolism.
Li J, Shao J, Zeng Z, He Y, Tang C, Park SH, Lee JH, Liu R. Li J, et al. Cell Death Differ. 2022 Jan;29(1):206-217. doi: 10.1038/s41418-021-00851-7. Epub 2021 Aug 31. Cell Death Differ. 2022. PMID: 34465890 Free PMC article.
Soft ECM results in TNF receptor-associated factor 2 (TRAF2)-dependent K29 ubiquitination and degradation of phosphoribosyl pyrophosphate synthetase (PRPS)1/2. Recruitment of TRAF2 to PRPS1/2 requires phosphorylation of PRPS1 S285 or PRPS2 T285, which is mediated by …
Soft ECM results in TNF receptor-associated factor 2 (TRAF2)-dependent K29 ubiquitination and degradation of phosphoribosyl pyroph
Ornithine carbamoyltransferase deficiency.
Wraith JE. Wraith JE. Arch Dis Child. 2001 Jan;84(1):84-88. doi: 10.1136/adc.84.1.84. Arch Dis Child. 2001. PMID: 11124797 Free PMC article. Review. No abstract available.
[PRPP synthetase superactivity].
Kawasugi K, Takeuchi F. Kawasugi K, et al. Nihon Rinsho. 2003 Jan;61 Suppl 1:284-7. Nihon Rinsho. 2003. PMID: 12629732 Review. Japanese. No abstract available.
Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.
Hove-Jensen B, Andersen KR, Kilstrup M, Martinussen J, Switzer RL, Willemoës M. Hove-Jensen B, et al. Microbiol Mol Biol Rev. 2016 Dec 28;81(1):e00040-16. doi: 10.1128/MMBR.00040-16. Print 2017 Mar. Microbiol Mol Biol Rev. 2016. PMID: 28031352 Free PMC article. Review.
Phosphoribosyl diphosphate (PRPP) is an important intermediate in cellular metabolism. ...
Phosphoribosyl diphosphate (PRPP) is an important intermediate in cellular metabolism. ...
Metabolic network of nucleosides in the brain.
Ipata PL, Camici M, Micheli V, Tozz MG. Ipata PL, et al. Curr Top Med Chem. 2011;11(8):909-22. doi: 10.2174/156802611795347555. Curr Top Med Chem. 2011. PMID: 21401502 Review.
Finally, phosphorolysis of brain nucleosides generates pentose phosphates, which are utilised for nucleoside interconversion, 5-phosphoribosyl-1-pyrophosphate synthesis, and energy repletion. This review focuses on these aspects of brain nucleoside metabolism, with …
Finally, phosphorolysis of brain nucleosides generates pentose phosphates, which are utilised for nucleoside interconversion, 5-phosphori
1,231 results