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Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system.
Fujii T, Pichel JG, Taira M, Toyama R, Dawid IB, Westphal H. Fujii T, et al. Among authors: pichel jg. Dev Dyn. 1994 Jan;199(1):73-83. doi: 10.1002/aja.1001990108. Dev Dyn. 1994. PMID: 7909459
GDNF is required for kidney development and enteric innervation.
Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. Pichel JG, et al. Cold Spring Harb Symp Quant Biol. 1996;61:445-57. Cold Spring Harb Symp Quant Biol. 1996. PMID: 9246473 No abstract available.
Defects in enteric innervation and kidney development in mice lacking GDNF.
Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. Pichel JG, et al. Nature. 1996 Jul 4;382(6586):73-6. doi: 10.1038/382073a0. Nature. 1996. PMID: 8657307
Timing of SV40 oncogene activation by site-specific recombination determines subsequent tumor progression during murine lens development.
Pichel JG, Lakso M, Westphal H. Pichel JG, et al. Oncogene. 1993 Dec;8(12):3333-42. Oncogene. 1993. PMID: 8247535
An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.
Nakamura T, Pichel JG, Williams-Simons L, Westphal H. Nakamura T, et al. Among authors: pichel jg. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):6142-6. doi: 10.1073/pnas.92.13.6142. Proc Natl Acad Sci U S A. 1995. PMID: 7597093 Free PMC article.
A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.
Farrell CM, Grinberg A, Huang SP, Chen D, Pichel JG, Westphal H, Felsenfeld G. Farrell CM, et al. Among authors: pichel jg. Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14554-9. doi: 10.1073/pnas.97.26.14554. Proc Natl Acad Sci U S A. 2000. PMID: 11121056 Free PMC article.
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.
Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, Lee E, Alt FW, Westphal H. Lakso M, et al. Among authors: pichel jg. Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5860-5. doi: 10.1073/pnas.93.12.5860. Proc Natl Acad Sci U S A. 1996. PMID: 8650183 Free PMC article.
Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice.
Shen L, Pichel JG, Mayeli T, Sariola H, Lu B, Westphal H. Shen L, et al. Among authors: pichel jg. Am J Hum Genet. 2002 Feb;70(2):435-47. doi: 10.1086/338712. Epub 2002 Jan 3. Am J Hum Genet. 2002. PMID: 11774071 Free PMC article.
Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse.
Srivastava M, Atwater I, Glasman M, Leighton X, Goping G, Caohuy H, Miller G, Pichel J, Westphal H, Mears D, Rojas E, Pollard HB. Srivastava M, et al. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13783-8. doi: 10.1073/pnas.96.24.13783. Proc Natl Acad Sci U S A. 1999. PMID: 10570150 Free PMC article.
Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies.
Granholm AC, Srivastava N, Mott JL, Henry S, Henry M, Westphal H, Pichel JG, Shen L, Hoffer BJ. Granholm AC, et al. Among authors: pichel jg. J Neurosci. 1997 Feb 1;17(3):1168-78. doi: 10.1523/JNEUROSCI.17-03-01168.1997. J Neurosci. 1997. PMID: 8994069 Free PMC article.
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