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Mechanisms underlying ubiquitination.
Pickart CM. Pickart CM. Annu Rev Biochem. 2001;70:503-33. doi: 10.1146/annurev.biochem.70.1.503. Annu Rev Biochem. 2001. PMID: 11395416 Review.
Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling.
Varadan R, Assfalg M, Haririnia A, Raasi S, Pickart C, Fushman D. Varadan R, et al. J Biol Chem. 2004 Feb 20;279(8):7055-63. doi: 10.1074/jbc.M309184200. Epub 2003 Nov 25. J Biol Chem. 2004. PMID: 14645257
., and Pickart, C. M. (1992) J. Biol. Chem. 267, 16467-16471; Varadan, R., Walker, O., Pickart, C., and Fushman, D. (2002) J. ...
., and Pickart, C. M. (1992) J. Biol. Chem. 267, 16467-16471; Varadan, R., Walker, O., Pickart, C., and Fushman, D. (2002) J. …
Functional dissection of a HECT ubiquitin E3 ligase.
Lu JY, Lin YY, Qian J, Tao SC, Zhu J, Pickart C, Zhu H. Lu JY, et al. Mol Cell Proteomics. 2008 Jan;7(1):35-45. doi: 10.1074/mcp.M700353-MCP200. Epub 2007 Oct 19. Mol Cell Proteomics. 2008. PMID: 17951556 Free PMC article.
Ubiquitin enters the new millennium.
Pickart CM. Pickart CM. Mol Cell. 2001 Sep;8(3):499-504. doi: 10.1016/s1097-2765(01)00347-1. Mol Cell. 2001. PMID: 11583613 Review.
Recognition of the polyubiquitin proteolytic signal.
Thrower JS, Hoffman L, Rechsteiner M, Pickart CM. Thrower JS, et al. EMBO J. 2000 Jan 4;19(1):94-102. doi: 10.1093/emboj/19.1.94. EMBO J. 2000. PMID: 10619848 Free PMC article.
Core domain mutation (S86Y) selectively inactivates polyubiquitin chain synthesis catalyzed by E2-25K.
Mastrandrea LD, Kasperek EM, Niles EG, Pickart CM. Mastrandrea LD, et al. Biochemistry. 1998 Jul 7;37(27):9784-92. doi: 10.1021/bi9800911. Biochemistry. 1998. PMID: 9657692
., and Pickart, C. M. (1997) Biochemistry 36, 10526-10537]. In the present study, we provide strong support for this model by showing that a point mutation in the core domain (S86Y) mimics the effect of deleting the entire tail domain: the ability to form an E2 approximate …
., and Pickart, C. M. (1997) Biochemistry 36, 10526-10537]. In the present study, we provide strong support for this model by showing …
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