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Pathogenesis of HIV infection: what the virus spares is as important as what it destroys.
Grossman Z, Meier-Schellersheim M, Paul WE, Picker LJ. Grossman Z, et al. Among authors: picker lj. Nat Med. 2006 Mar;12(3):289-95. doi: 10.1038/nm1380. Nat Med. 2006. PMID: 16520776
Roadblocks to translational challenges on viral pathogenesis.
Deeks S, Drosten C, Picker L, Subbarao K, Suzich J. Deeks S, et al. Among authors: picker l. Nat Med. 2013 Jan;19(1):30-4. doi: 10.1038/nm.3050. Nat Med. 2013. PMID: 23296014 Free PMC article.
Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques.
Hel Z, Nacsa J, Kelsall B, Tsai WP, Letvin N, Parks RW, Tryniszewska E, Picker L, Lewis MG, Edghill-Smith Y, Moniuszko M, Pal R, Stevceva L, Altman JD, Allen TM, Watkins D, Torres JV, Berzofsky JA, Belyakov IM, Strober W, Franchini G. Hel Z, et al. Among authors: picker l. J Virol. 2001 Dec;75(23):11483-95. doi: 10.1128/JVI.75.23.11483-11495.2001. J Virol. 2001. PMID: 11689630 Free PMC article.
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.
Okoye AA, Hansen SG, Vaidya M, Fukazawa Y, Park H, Duell DM, Lum R, Hughes CM, Ventura AB, Ainslie E, Ford JC, Morrow D, Gilbride RM, Legasse AW, Hesselgesser J, Geleziunas R, Li Y, Oswald K, Shoemaker R, Fast R, Bosche WJ, Borate BR, Edlefsen PT, Axthelm MK, Picker LJ, Lifson JD. Okoye AA, et al. Among authors: picker lj. Nat Med. 2018 Sep;24(9):1430-1440. doi: 10.1038/s41591-018-0130-7. Epub 2018 Aug 6. Nat Med. 2018. PMID: 30082858 Free PMC article.
Another HIV vaccine failure: where to next?
McMichael A, Picker LJ, Moore JP, Burton DR. McMichael A, et al. Among authors: picker lj. Nat Med. 2013 Dec;19(12):1576-7. doi: 10.1038/nm.3413. Nat Med. 2013. PMID: 24309655 No abstract available.
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine.
Hansen SG, Zak DE, Xu G, Ford JC, Marshall EE, Malouli D, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Randall KT, Selseth AN, Rundstrom P, Herlache L, Lewis MS, Park H, Planer SL, Turner JM, Fischer M, Armstrong C, Zweig RC, Valvo J, Braun JM, Shankar S, Lu L, Sylwester AW, Legasse AW, Messerle M, Jarvis MA, Amon LM, Aderem A, Alter G, Laddy DJ, Stone M, Bonavia A, Evans TG, Axthelm MK, Früh K, Edlefsen PT, Picker LJ. Hansen SG, et al. Among authors: picker lj. Nat Med. 2018 Feb;24(2):130-143. doi: 10.1038/nm.4473. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334373 Free PMC article.
Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.
Fukazawa Y, Park H, Cameron MJ, Lefebvre F, Lum R, Coombes N, Mahyari E, Hagen SI, Bae JY, Reyes MD 3rd, Swanson T, Legasse AW, Sylwester A, Hansen SG, Smith AT, Stafova P, Shoemaker R, Li Y, Oswald K, Axthelm MK, McDermott A, Ferrari G, Montefiori DC, Edlefsen PT, Piatak M Jr, Lifson JD, Sékaly RP, Picker LJ. Fukazawa Y, et al. Among authors: picker lj. Nat Med. 2012 Nov;18(11):1673-81. doi: 10.1038/nm.2934. Epub 2012 Sep 9. Nat Med. 2012. PMID: 22961108 Free PMC article.
New paradigms for HIV/AIDS vaccine development.
Picker LJ, Hansen SG, Lifson JD. Picker LJ, et al. Annu Rev Med. 2012;63:95-111. doi: 10.1146/annurev-med-042010-085643. Epub 2011 Sep 19. Annu Rev Med. 2012. PMID: 21942424 Free PMC article. Review.
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine.
Hansen SG, Ford JC, Lewis MS, Ventura AB, Hughes CM, Coyne-Johnson L, Whizin N, Oswald K, Shoemaker R, Swanson T, Legasse AW, Chiuchiolo MJ, Parks CL, Axthelm MK, Nelson JA, Jarvis MA, Piatak M Jr, Lifson JD, Picker LJ. Hansen SG, et al. Among authors: picker lj. Nature. 2011 May 26;473(7348):523-7. doi: 10.1038/nature10003. Epub 2011 May 11. Nature. 2011. PMID: 21562493 Free PMC article.
Glycosylation of simian immunodeficiency virus influences immune-tissue targeting during primary infection, leading to immunodeficiency or viral control.
Sugimoto C, Nakamura S, Hagen SI, Tsunetsugu-Yokota Y, Villinger F, Ansari AA, Suzuki Y, Yamamoto N, Nagai Y, Picker LJ, Mori K. Sugimoto C, et al. Among authors: picker lj. J Virol. 2012 Sep;86(17):9323-36. doi: 10.1128/JVI.00948-12. Epub 2012 Jun 20. J Virol. 2012. PMID: 22718828 Free PMC article.
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