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RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction.
Liesman RM, Buchholz UJ, Luongo CL, Yang L, Proia AD, DeVincenzo JP, Collins PL, Pickles RJ. Liesman RM, et al. Among authors: pickles rj. J Clin Invest. 2014 May;124(5):2219-33. doi: 10.1172/JCI72948. Epub 2014 Apr 8. J Clin Invest. 2014. PMID: 24713657 Free PMC article. Clinical Trial.
RSV604, a novel inhibitor of respiratory syncytial virus replication.
Chapman J, Abbott E, Alber DG, Baxter RC, Bithell SK, Henderson EA, Carter MC, Chambers P, Chubb A, Cockerill GS, Collins PL, Dowdell VC, Keegan SJ, Kelsey RD, Lockyer MJ, Luongo C, Najarro P, Pickles RJ, Simmonds M, Taylor D, Tyms S, Wilson LJ, Powell KL. Chapman J, et al. Among authors: pickles rj. Antimicrob Agents Chemother. 2007 Sep;51(9):3346-53. doi: 10.1128/AAC.00211-07. Epub 2007 Jun 18. Antimicrob Agents Chemother. 2007. PMID: 17576833 Free PMC article.
Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates.
Bartlett EJ, Cruz AM, Esker J, Castaño A, Schomacker H, Surman SR, Hennessey M, Boonyaratanakornkit J, Pickles RJ, Collins PL, Murphy BR, Schmidt AC. Bartlett EJ, et al. Among authors: pickles rj. J Virol. 2008 Sep;82(18):8965-77. doi: 10.1128/JVI.00853-08. Epub 2008 Jul 9. J Virol. 2008. PMID: 18614629 Free PMC article.
Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge.
Bukreyev A, Marzi A, Feldmann F, Zhang L, Yang L, Ward JM, Dorward DW, Pickles RJ, Murphy BR, Feldmann H, Collins PL. Bukreyev A, et al. Among authors: pickles rj. Virology. 2009 Jan 20;383(2):348-61. doi: 10.1016/j.virol.2008.09.030. Epub 2008 Nov 17. Virology. 2009. PMID: 19010509 Free PMC article.
MAVS-mediated apoptosis and its inhibition by viral proteins.
Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. Lei Y, et al. Among authors: pickles rj. PLoS One. 2009;4(5):e5466. doi: 10.1371/journal.pone.0005466. Epub 2009 Mar 7. PLoS One. 2009. PMID: 19404494 Free PMC article.
96 results