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High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model.
Mondal S, Hegarty E, Sahn JJ, Scott LL, Gökçe SK, Martin C, Ghorashian N, Satarasinghe PN, Iyer S, Sae-Lee W, Hodges TR, Pierce JT, Martin SF, Ben-Yakar A. Mondal S, et al. Among authors: pierce jt. ACS Chem Neurosci. 2018 May 16;9(5):1014-1026. doi: 10.1021/acschemneuro.7b00428. Epub 2018 Feb 23. ACS Chem Neurosci. 2018. PMID: 29426225 Free PMC article.
Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors.
Scott LL, Sahn JJ, Ferragud A, Yen RC, Satarasinghe PN, Wood MD, Hodges TR, Shi T, Prakash BA, Friese KM, Shen A, Sabino V, Pierce JT, Martin SF. Scott LL, et al. Among authors: pierce jt. Neuropsychopharmacology. 2018 Aug;43(9):1867-1875. doi: 10.1038/s41386-018-0067-z. Epub 2018 Apr 20. Neuropsychopharmacology. 2018. PMID: 29728649 Free PMC article.
A Novel Peptide Restricts Ethanol Modulation of the BK Channel In Vitro and In Vivo.
Scott LL, Iyer S, Philpo AE, Avalos MN, Wu NS, Shi T, Prakash BA, Nguyen TT, Mihic SJ, Aldrich RW, Pierce JT. Scott LL, et al. Among authors: pierce jt. J Pharmacol Exp Ther. 2018 Nov;367(2):282-290. doi: 10.1124/jpet.118.251918. Epub 2018 Aug 29. J Pharmacol Exp Ther. 2018. PMID: 30158242 Free PMC article.
96 results