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Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
Fomovska A, Huang Q, El Bissati K, Mui EJ, Witola WH, Cheng G, Zhou Y, Sommerville C, Roberts CW, Bettis S, Prigge ST, Afanador GA, Hickman MR, Lee PJ, Leed SE, Auschwitz JM, Pieroni M, Stec J, Muench SP, Rice DW, Kozikowski AP, McLeod R. Fomovska A, et al. Among authors: pieroni m. Antimicrob Agents Chemother. 2012 May;56(5):2666-82. doi: 10.1128/AAC.06450-11. Epub 2012 Feb 21. Antimicrob Agents Chemother. 2012. PMID: 22354304 Free PMC article.
Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania.
Stec J, Huang Q, Pieroni M, Kaiser M, Fomovska A, Mui E, Witola WH, Bettis S, McLeod R, Brun R, Kozikowski AP. Stec J, et al. Among authors: pieroni m. J Med Chem. 2012 Apr 12;55(7):3088-100. doi: 10.1021/jm2015183. Epub 2012 Mar 20. J Med Chem. 2012. PMID: 22352841 Free PMC article.
In pursuit of natural product leads: synthesis and biological evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and its analogues: discovery of N-(2-benzoxazol-2-ylphenyl)benzamides as novel antileishmanial chemotypes.
Tipparaju SK, Joyasawal S, Pieroni M, Kaiser M, Brun R, Kozikowski AP. Tipparaju SK, et al. Among authors: pieroni m. J Med Chem. 2008 Dec 11;51(23):7344-7. doi: 10.1021/jm801241n. J Med Chem. 2008. PMID: 18989953
Preliminary structure-activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains.
Onajole OK, Pieroni M, Tipparaju SK, Lun S, Stec J, Chen G, Gunosewoyo H, Guo H, Ammerman NC, Bishai WR, Kozikowski AP. Onajole OK, et al. Among authors: pieroni m. J Med Chem. 2013 May 23;56(10):4093-103. doi: 10.1021/jm4003878. Epub 2013 May 3. J Med Chem. 2013. PMID: 23611124
283 results