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Cellular imaging using matrix-enhanced and metal-assisted SIMS.
Altelaar AF, Piersma SR. Altelaar AF, et al. Methods Mol Biol. 2010;656:197-208. doi: 10.1007/978-1-60761-746-4_11. Methods Mol Biol. 2010. PMID: 20680592
Imaging mass spectrometry at cellular length scales.
Altelaar AF, Luxembourg SL, McDonnell LA, Piersma SR, Heeren RM. Altelaar AF, et al. Nat Protoc. 2007;2(5):1185-96. doi: 10.1038/nprot.2007.117. Nat Protoc. 2007. PMID: 17546014
Subcellular imaging mass spectrometry of brain tissue.
McDonnell LA, Piersma SR, MaartenAltelaar AF, Mize TH, Luxembourg SL, Verhaert PD, van Minnen J, Heeren RM. McDonnell LA, et al. J Mass Spectrom. 2005 Feb;40(2):160-8. doi: 10.1002/jms.735. J Mass Spectrom. 2005. PMID: 15706616
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.
Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Van Houdt WJ, et al. Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25. Mol Cell Proteomics. 2011. PMID: 21788403 Free PMC article.
Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.
Rajcevic U, Knol JC, Piersma S, Bougnaud S, Fack F, Sundlisaeter E, Søndenaa K, Myklebust R, Pham TV, Niclou SP, Jiménez CR. Rajcevic U, et al. Proteome Sci. 2014 Jul 11;12:39. doi: 10.1186/1477-5956-12-39. eCollection 2014. Proteome Sci. 2014. PMID: 25075203 Free PMC article.
Sunitinib activates Axl signaling in renal cell cancer.
van der Mijn JC, Broxterman HJ, Knol JC, Piersma SR, De Haas RR, Dekker H, Pham TV, Van Beusechem VW, Halmos B, Mier JW, Jiménez CR, Verheul HM. van der Mijn JC, et al. Int J Cancer. 2016 Jun 15;138(12):3002-10. doi: 10.1002/ijc.30022. Epub 2016 Mar 1. Int J Cancer. 2016. PMID: 26815723
Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
De Vries-van Leeuwen IJ, da Costa Pereira D, Flach KD, Piersma SR, Haase C, Bier D, Yalcin Z, Michalides R, Feenstra KA, Jiménez CR, de Greef TF, Brunsveld L, Ottmann C, Zwart W, de Boer AH. De Vries-van Leeuwen IJ, et al. Proc Natl Acad Sci U S A. 2013 May 28;110(22):8894-9. doi: 10.1073/pnas.1220809110. Epub 2013 May 15. Proc Natl Acad Sci U S A. 2013. PMID: 23676274 Free PMC article.
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