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The jejunum of diarrhea-predominant irritable bowel syndrome shows molecular alterations in the tight junction signaling pathway that are associated with mucosal pathobiology and clinical manifestations.
Martínez C, Vicario M, Ramos L, Lobo B, Mosquera JL, Alonso C, Sánchez A, Guilarte M, Antolín M, de Torres I, González-Castro AM, Pigrau M, Saperas E, Azpiroz F, Santos J. Martínez C, et al. Among authors: pigrau m. Am J Gastroenterol. 2012 May;107(5):736-46. doi: 10.1038/ajg.2011.472. Epub 2012 Mar 13. Am J Gastroenterol. 2012. PMID: 22415197
Acute experimental stress evokes a differential gender-determined increase in human intestinal macromolecular permeability.
Alonso C, Guilarte M, Vicario M, Ramos L, Rezzi S, Martínez C, Lobo B, Martin FP, Pigrau M, González-Castro AM, Gallart M, Malagelada JR, Azpiroz F, Kochhar S, Santos J. Alonso C, et al. Among authors: pigrau m. Neurogastroenterol Motil. 2012 Aug;24(8):740-6, e348-9. doi: 10.1111/j.1365-2982.2012.01928.x. Epub 2012 May 24. Neurogastroenterol Motil. 2012. PMID: 22625665
Intestinal barrier function and the brain-gut axis.
Alonso C, Vicario M, Pigrau M, Lobo B, Santos J. Alonso C, et al. Among authors: pigrau m. Adv Exp Med Biol. 2014;817:73-113. doi: 10.1007/978-1-4939-0897-4_4. Adv Exp Med Biol. 2014. PMID: 24997030 Review.
Increased humoral immunity in the jejunum of diarrhoea-predominant irritable bowel syndrome associated with clinical manifestations.
Vicario M, González-Castro AM, Martínez C, Lobo B, Pigrau M, Guilarte M, de Torres I, Mosquera JL, Fortea M, Sevillano-Aguilera C, Salvo-Romero E, Alonso C, Rodiño-Janeiro BK, Söderholm JD, Azpiroz F, Santos J. Vicario M, et al. Among authors: pigrau m. Gut. 2015 Sep;64(9):1379-88. doi: 10.1136/gutjnl-2013-306236. Epub 2014 Sep 10. Gut. 2015. PMID: 25209656
Role of Corticotropin-releasing Factor in Gastrointestinal Permeability.
Rodiño-Janeiro BK, Alonso-Cotoner C, Pigrau M, Lobo B, Vicario M, Santos J. Rodiño-Janeiro BK, et al. Among authors: pigrau m. J Neurogastroenterol Motil. 2015 Jan 1;21(1):33-50. doi: 10.5056/jnm14084. J Neurogastroenterol Motil. 2015. PMID: 25537677 Free PMC article.
miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea.
Martínez C, Rodiño-Janeiro BK, Lobo B, Stanifer ML, Klaus B, Granzow M, González-Castro AM, Salvo-Romero E, Alonso-Cotoner C, Pigrau M, Roeth R, Rappold G, Huber W, González-Silos R, Lorenzo J, de Torres I, Azpiroz F, Boulant S, Vicario M, Niesler B, Santos J. Martínez C, et al. Among authors: pigrau m. Gut. 2017 Sep;66(9):1537-1538. doi: 10.1136/gutjnl-2016-311477. Epub 2017 Jan 12. Gut. 2017. PMID: 28082316 Free PMC article.
Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome.
Cremon C, Stanghellini V, Barbaro MR, Cogliandro RF, Bellacosa L, Santos J, Vicario M, Pigrau M, Alonso Cotoner C, Lobo B, Azpiroz F, Bruley des Varannes S, Neunlist M, DeFilippis D, Iuvone T, Petrosino S, Di Marzo V, Barbara G. Cremon C, et al. Among authors: pigrau m. Aliment Pharmacol Ther. 2017 Apr;45(7):909-922. doi: 10.1111/apt.13958. Epub 2017 Feb 6. Aliment Pharmacol Ther. 2017. PMID: 28164346 Clinical Trial.
22 results