Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

35 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
A conservative amino acid mutation in the chromosome-encoded dihydrofolate reductase confers trimethoprim resistance in Streptococcus pneumoniae.
Pikis A, Donkersloot JA, Rodriguez WJ, Keith JM. Pikis A, et al. J Infect Dis. 1998 Sep;178(3):700-6. doi: 10.1086/515371. J Infect Dis. 1998. PMID: 9728538
Comparison of DHFR sequences from pneumococcal strains with various susceptibilities to trimethoprim, together with site-directed mutagenesis, revealed that substitution of isoleucine-100 with a leucine residue resulted in trimethoprim resistance. Hydrogen bonding between …
Comparison of DHFR sequences from pneumococcal strains with various susceptibilities to trimethoprim, together with site-directed mutagenesi …
The gene CBO0515 from Clostridium botulinum strain Hall A encodes the rare enzyme N5-(carboxyethyl) ornithine synthase, EC 1.5.1.24.
Thompson J, Hill KK, Smith TJ, Pikis A. Thompson J, et al. J Bacteriol. 2010 Feb;192(4):1151-5. doi: 10.1128/JB.01044-09. Epub 2009 Nov 20. J Bacteriol. 2010. PMID: 19933367 Free PMC article.
Sequencing of the genome of Clostridium botulinum strain Hall A revealed a gene (CBO0515), whose putative amino acid sequence was suggestive of the rare enzyme N(5)-(1-carboxyethyl) ornithine synthase. ...
Sequencing of the genome of Clostridium botulinum strain Hall A revealed a gene (CBO0515), whose putative amino acid sequence …
Beta-glucoside kinase (BglK) from Klebsiella pneumoniae. Purification, properties, and preparative synthesis of 6-phospho-beta-D-glucosides.
Thompson J, Lichtenthaler FW, Peters S, Pikis A. Thompson J, et al. J Biol Chem. 2002 Sep 13;277(37):34310-21. doi: 10.1074/jbc.M206397200. Epub 2002 Jul 10. J Biol Chem. 2002. PMID: 12110692
In solution, the enzyme (EC ) exists as a homotetramer composed of non-covalently linked subunits of M(r) approximately 33,000. ...The open reading frame (ORF) of bglK encodes a 297-residue polypeptide of calculated M(r) 32,697. A motif of 7 amino acids (AFD( …
In solution, the enzyme (EC ) exists as a homotetramer composed of non-covalently linked subunits of M(r) approximately 33,000. ...Th …
Metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae. Participation and properties of sucrose-6-phosphate hydrolase and phospho-alpha-glucosidase.
Thompson J, Robrish SA, Immel S, Lichtenthaler FW, Hall BG, Pikis A. Thompson J, et al. J Biol Chem. 2001 Oct 5;276(40):37415-25. doi: 10.1074/jbc.M106504200. Epub 2001 Jul 25. J Biol Chem. 2001. PMID: 11473129
The aglB gene has been cloned and sequenced, and AglB (M(r) = 49,256) has been purified from a high expression system using the chromogenic p-nitrophenyl alpha-glucopyranoside 6-phosphate as substrate. ...The phospho-alpha-glucosidase gene (aglB) lies adjacent to a
The aglB gene has been cloned and sequenced, and AglB (M(r) = 49,256) has been purified from a high expression system using the chrom …
The gene glvA of Bacillus subtilis 168 encodes a metal-requiring, NAD(H)-dependent 6-phospho-alpha-glucosidase. Assignment to family 4 of the glycosylhydrolase superfamily.
Thompson J, Pikis A, Ruvinov SB, Henrissat B, Yamamoto H, Sekiguchi J. Thompson J, et al. J Biol Chem. 1998 Oct 16;273(42):27347-56. doi: 10.1074/jbc.273.42.27347. J Biol Chem. 1998. PMID: 9765262
The purified protein GlvA (449 residues, Mr = 50,513) is a unique 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolase (6-phospho-alpha-glucosidase) that requires both NAD(H) and divalent metal (Mn2+, Fe2+, Co2+, or Ni2+) for activity. 6-Phospho-alpha-glucosidase (E …
The purified protein GlvA (449 residues, Mr = 50,513) is a unique 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolase (6-phos …
Optochin resistance in Streptococcus pneumoniae: mechanism, significance, and clinical implications.
Pikis A, Campos JM, Rodriguez WJ, Keith JM. Pikis A, et al. J Infect Dis. 2001 Sep 1;184(5):582-90. doi: 10.1086/322803. Epub 2001 Jul 26. J Infect Dis. 2001. PMID: 11474432
Resistance arose from single point mutations in either the a-subunit (W206S) or the c-subunit (G20S, M23I, and A49T) of H(+)-ATPase. There is speculation of a possible association between exposure to antimalarial drugs and evolution of optochin resistance. alpha-Hem …
Resistance arose from single point mutations in either the a-subunit (W206S) or the c-subunit (G20S, M23I, and A49T) of H(+)-ATPase. …
Decreased susceptibility to imipenem among penicillin-resistant Streptococcus pneumoniae.
Pikis A, Donkersloot JA, Akram S, Keith JM, Campos JM, Rodriguez WJ. Pikis A, et al. J Antimicrob Chemother. 1997 Jul;40(1):105-8. doi: 10.1093/jac/40.1.105. J Antimicrob Chemother. 1997. PMID: 9249211
Phosphorylation and metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae.
Thompson J, Robrish SA, Pikis A, Brust A, Lichtenthaler FW. Thompson J, et al. Carbohydr Res. 2001 Mar 22;331(2):149-61. doi: 10.1016/s0008-6215(01)00028-3. Carbohydr Res. 2001. PMID: 11322729
Not only sucrose but the five isomeric alpha-D-glucosyl-D-fructoses trehalulose, turanose, maltulose, leucrose, and palatinose are utilized by Klebsiella pneumoniae as energy sources for growth, thereby undergoing phosphorylation by a phosphoenolpyruvate-dependent phosphot …
Not only sucrose but the five isomeric alpha-D-glucosyl-D-fructoses trehalulose, turanose, maltulose, leucrose, and palatinose are utilized …
Genes malh and pagl of Clostridium acetobutylicum ATCC 824 encode NAD+- and Mn2+-dependent phospho-alpha-glucosidase(s).
Thompson J, Hess S, Pikis A. Thompson J, et al. J Biol Chem. 2004 Jan 9;279(2):1553-61. doi: 10.1074/jbc.M310733200. Epub 2003 Oct 21. J Biol Chem. 2004. PMID: 14570887
C. acetobutylicum grows on a variety of alpha-linked glucosides, including maltose, methyl-alpha-d-glucoside, and the five isomers of sucrose. ...
C. acetobutylicum grows on a variety of alpha-linked glucosides, including maltose, methyl-alpha-d-glucoside, and the five isomers of …
Resistance of human cytomegalovirus to ganciclovir/valganciclovir: a comprehensive review of putative resistance pathways.
Komatsu TE, Pikis A, Naeger LK, Harrington PR. Komatsu TE, et al. Among authors: pikis a. Antiviral Res. 2014 Jan;101:12-25. doi: 10.1016/j.antiviral.2013.10.011. Epub 2013 Oct 31. Antiviral Res. 2014. PMID: 24184129 Review.
35 results
Jump to page
Feedback