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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 6
1969 1
1970 7
1971 20
1972 34
1973 40
1974 72
1975 104
1976 116
1977 115
1978 127
1979 113
1980 96
1981 82
1982 111
1983 88
1984 91
1985 92
1986 98
1987 75
1988 62
1989 71
1990 61
1991 39
1992 44
1993 59
1994 46
1995 30
1996 40
1997 42
1998 25
1999 31
2000 40
2001 36
2002 26
2003 31
2004 31
2005 31
2006 29
2007 16
2008 26
2009 28
2010 31
2011 15
2012 26
2013 33
2014 18
2015 21
2016 24
2017 24
2018 30
2019 31
2020 30
2021 33
2022 38
2023 31
2024 12

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Search Results

2,658 results

Results by year

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Page 1
Ponatinib and STAT5 Inhibitor Pimozide Combined Synergistic Treatment Applications Potentially Overcome Drug Resistance via Regulating the Cytokine Expressional Network in Chronic Myeloid Leukemia Cells.
Tezcanli Kaymaz B, Gumus N, Celik B, Alcitepe İ, Biray Avci C, Aktan C. Tezcanli Kaymaz B, et al. J Interferon Cytokine Res. 2024 Apr;44(4):178-189. doi: 10.1089/jir.2023.0170. J Interferon Cytokine Res. 2024. PMID: 38579140
Protein-protein interaction analysis showed that IL2, IL6, IL15, IFNG, and others appeared in the top lists of pathways, indicating their high centrality and importance in the network. Therefore, pimozide could be a promising agent to support TKI therapies in ponatinib res …
Protein-protein interaction analysis showed that IL2, IL6, IL15, IFNG, and others appeared in the top lists of pathways, indicating their hi …
Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention.
Dai F, Hu C, Li X, Zhang Z, Wang H, Zhou W, Wang J, Geng Q, Dong Y, Tang C. Dai F, et al. Neural Regen Res. 2024 Nov 1;19(11):2480-2487. doi: 10.4103/1673-5374.390966. Epub 2023 Dec 15. Neural Regen Res. 2024. PMID: 38526284 Free article.
Cav3.2 channel is a main subtype of T-type calcium channels. T-type calcium channel blockers, such as pimozide and mibefradil, have been shown to prevent cerebral ischemia/reperfusion injury-induced brain injury. ...
Cav3.2 channel is a main subtype of T-type calcium channels. T-type calcium channel blockers, such as pimozide and mibefradil, have b …
Withdrawal syndrome after antipsychotics discontinuation: an analysis of the WHO database of spontaneous reports (Vigibase) between 2000 and 2022.
Storck W, de Laportalière TT, Yrondi A, Javelot H, Berna F, Montastruc F. Storck W, et al. Psychopharmacology (Berl). 2024 Feb 20. doi: 10.1007/s00213-024-06554-4. Online ahead of print. Psychopharmacology (Berl). 2024. PMID: 38376511
Tiotixene had the highest risk of reporting WDS (ROR 7.08; 95%CI 3.49 - 14.35) followed by pimozide (ROR 4.35; 95%CI 1.93 - 9.77), quetiapine (ROR 4.24; 95%CI 3.87 - 4.64), thioridazine (ROR 4.17; 95%CI 2.50-6.98) and ziprasidone (ROR 2.98; 95%CI 2.41-3.67). ...CONCLUSION: …
Tiotixene had the highest risk of reporting WDS (ROR 7.08; 95%CI 3.49 - 14.35) followed by pimozide (ROR 4.35; 95%CI 1.93 - 9.77), qu …
Unlocking therapeutic potential: computational insights into TREM2 protein targeting with FDA-approved drugs for neurodegeneration.
Alrouji M, Yasmin S, Alhumaydhi FA, Sharaf SE, Shahwan M, Shamsi A. Alrouji M, et al. J Biomol Struct Dyn. 2024 Feb 19:1-11. doi: 10.1080/07391102.2024.2317987. Online ahead of print. J Biomol Struct Dyn. 2024. PMID: 38373093
Among the repurposed drugs identified in the initial screening, Carpipramine, Clocapramine, and Pimozide stood out due to their notable binding potential and favorable drug profiling. ...The findings revealed that the elucidated molecules, Carpipramine, Clocapramine, and …
Among the repurposed drugs identified in the initial screening, Carpipramine, Clocapramine, and Pimozide stood out due to their notab …
The antipsychotic drug pimozide promotes apoptosis through the RAF/ERK pathway and enhances autophagy in breast cancer cells.
Jiang G, Zhou X, Hu Y, Tan X, Wang D, Yang L, Zhang Q, Liu S. Jiang G, et al. Cancer Biol Ther. 2024 Dec 31;25(1):2302413. doi: 10.1080/15384047.2024.2302413. Epub 2024 Feb 14. Cancer Biol Ther. 2024. PMID: 38356266 Free PMC article.
The antipsychotic drug pimozide has been demonstrated to inhibit cancer. However, the precise anti-cancer mechanism of pimozide remains unclear. ...The knockdown of RAF1 expression induced autophagy and apoptosis in breast cancer cells, consistent with the results o …
The antipsychotic drug pimozide has been demonstrated to inhibit cancer. However, the precise anti-cancer mechanism of pimozide …
Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment.
Li J, Hua Y, Liu Y, Qu X, Zhang J, Ishida M, Yoshida N, Tabata A, Miyoshi H, Shiba M, Higo S, Sougawa N, Takeda M, Kawamura T, Matsuura R, Okuzaki D, Toyofuku T, Sawa Y, Liu L, Miyagawa S. Li J, et al. iScience. 2024 Jan 23;27(2):108992. doi: 10.1016/j.isci.2024.108992. eCollection 2024 Feb 16. iScience. 2024. PMID: 38333703 Free PMC article.
Notably, the TW group displayed increased arrhythmia rates with high and intermediate risk TdP drugs (quinidine and pimozide), underscoring the potential utility of this system in drug assessment applications....
Notably, the TW group displayed increased arrhythmia rates with high and intermediate risk TdP drugs (quinidine and pimozide), unders …
Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity.
Alkafaas SS, Abdallah AM, Hassan MH, Hussien AM, Elkafas SS, Loutfy SA, Mikhail A, Murad OG, Elsalahaty MI, Hessien M, Elshazli RM, Alsaeed FA, Ahmed AE, Kamal HK, Hafez W, El-Saadony MT, El-Tarabily KA, Ghosh S. Alkafaas SS, et al. BMC Public Health. 2024 Feb 6;24(1):395. doi: 10.1186/s12889-024-17747-z. BMC Public Health. 2024. PMID: 38321448 Free PMC article. Review.
In silico molecular docking analyses of FIASMAs with inhibitors revealed that dilazep (S = - 12.58 kcal/mol), emetine (S = - 11.65 kcal/mol), pimozide (S = - 11.29 kcal/mol), carvedilol (S = - 11.28 kcal/mol), mebeverine (S = - 11.14 kcal/mol), cepharanthine (S = - 11.06 k …
In silico molecular docking analyses of FIASMAs with inhibitors revealed that dilazep (S = - 12.58 kcal/mol), emetine (S = - 11.65 kcal/mol) …
BDH1-mediated LRRC31 regulation dependent on histone lysine β-hydroxybutyrylation to promote lung adenocarcinoma progression.
Huang J, Liang L, Jiang S, Liu Y, He H, Sun X, Li Y, Xie L, Tao Y, Cong L, Jiang Y. Huang J, et al. MedComm (2020). 2023 Dec 13;4(6):e449. doi: 10.1002/mco2.449. eCollection 2023 Dec. MedComm (2020). 2023. PMID: 38098610 Free PMC article.
Furthermore, we identified potential BDH1 inhibitors, namely pimozide and crizotinib, which exhibit a synergistic inhibitory effect on the proliferation of LUAD cells exhibiting high expression of BDH1. ...
Furthermore, we identified potential BDH1 inhibitors, namely pimozide and crizotinib, which exhibit a synergistic inhibitory effect o …
99mTc(CO)3-labeled 1-(2-Pyridyl)piperazine derivatives as radioligands for 5-HT7 receptors.
Mardanshahi A, Vaseghi S, Hosseinimehr SJ, Abedi SM, Molavipordanjani S. Mardanshahi A, et al. Ann Nucl Med. 2024 Feb;38(2):139-153. doi: 10.1007/s12149-023-01885-2. Epub 2023 Nov 30. Ann Nucl Med. 2024. PMID: 38032496
The data of the biodistribution study in the U87-MG xenograft model revealed that these radiotracers could accumulate in the tumor site, and the highest tumor uptake was observed at 60 min post-injection (3.38 0.65 and 3.27 0.5%ID/g, respectively). The injection of pimozide …
The data of the biodistribution study in the U87-MG xenograft model revealed that these radiotracers could accumulate in the tumor site, and …
2,658 results