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Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.
Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, Yarden Y. Shtiegman K, et al. Among authors: pines g. Oncogene. 2007 Oct 25;26(49):6968-78. doi: 10.1038/sj.onc.1210503. Epub 2007 May 7. Oncogene. 2007. PMID: 17486068
Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression.
Pareja F, Ferraro DA, Rubin C, Cohen-Dvashi H, Zhang F, Aulmann S, Ben-Chetrit N, Pines G, Navon R, Crosetto N, Köstler W, Carvalho S, Lavi S, Schmitt F, Dikic I, Yakhini Z, Sinn P, Mills GB, Yarden Y. Pareja F, et al. Among authors: pines g. Oncogene. 2012 Oct 25;31(43):4599-608. doi: 10.1038/onc.2011.587. Epub 2011 Dec 19. Oncogene. 2012. PMID: 22179831 Free PMC article.
Kinase-mediated quasi-dimers of EGFR.
Bublil EM, Pines G, Patel G, Fruhwirth G, Ng T, Yarden Y. Bublil EM, et al. Among authors: pines g. FASEB J. 2010 Dec;24(12):4744-55. doi: 10.1096/fj.10-166199. Epub 2010 Aug 3. FASEB J. 2010. PMID: 20682838 Free PMC article.
EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.
Tarcic G, Avraham R, Pines G, Amit I, Shay T, Lu Y, Zwang Y, Katz M, Ben-Chetrit N, Jacob-Hirsch J, Virgilio L, Rechavi G, Mavrothalassitis G, Mills GB, Domany E, Yarden Y. Tarcic G, et al. Among authors: pines g. FASEB J. 2012 Apr;26(4):1582-92. doi: 10.1096/fj.11-194654. Epub 2011 Dec 23. FASEB J. 2012. PMID: 22198386 Free PMC article.
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.
Roth L, Srivastava S, Lindzen M, Sas-Chen A, Sheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y. Roth L, et al. Among authors: pines g. Sci Signal. 2018 Jan 30;11(515):eaan0949. doi: 10.1126/scisignal.aan0949. Sci Signal. 2018. PMID: 29382783
65 results