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Crystal structure of dihydroorotate dehydrogenase from Leishmania major.
Cordeiro AT, Feliciano PR, Pinheiro MP, Nonato MC. Cordeiro AT, et al. Among authors: pinheiro mp. Biochimie. 2012 Aug;94(8):1739-48. doi: 10.1016/j.biochi.2012.04.003. Epub 2012 Apr 21. Biochimie. 2012. PMID: 22542640
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain.
Pinheiro MP, Iulek J, Cristina Nonato M. Pinheiro MP, et al. Biochem Biophys Res Commun. 2008 May 9;369(3):812-7. doi: 10.1016/j.bbrc.2008.02.074. Epub 2008 Feb 25. Biochem Biophys Res Commun. 2008. PMID: 18302934
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the N-terminal carbohydrate-recognition domain of human galectin-4.
Zimbardi AL, Pinheiro MP, Dias-Baruffi M, Nonato MC. Zimbardi AL, et al. Among authors: pinheiro mp. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):542-5. doi: 10.1107/S1744309110010778. Epub 2010 Apr 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20445255 Free PMC article.
Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery.
Cheleski J, Rocha JR, Pinheiro MP, Wiggers HJ, da Silva AB, Nonato MC, Montanari CA. Cheleski J, et al. Among authors: pinheiro mp. Eur J Med Chem. 2010 Dec;45(12):5899-909. doi: 10.1016/j.ejmech.2010.09.055. Epub 2010 Oct 7. Eur J Med Chem. 2010. PMID: 20965617
Crystallization and preliminary X-ray diffraction analysis of recombinant chlorocatechol 1,2-dioxygenase from Pseudomonas putida.
Rustiguel JK, Pinheiro MP, Araújo AP, Nonato MC. Rustiguel JK, et al. Among authors: pinheiro mp. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Apr 1;67(Pt 4):507-9. doi: 10.1107/S174430911100635X. Epub 2011 Mar 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21505253 Free PMC article.
Target sites for the design of anti-trypanosomatid drugs based on the structure of dihydroorotate dehydrogenase.
Pinheiro MP, Emery Fda S, Nonato MC. Pinheiro MP, et al. Curr Pharm Des. 2013;19(14):2615-27. doi: 10.2174/1381612811319140011. Curr Pharm Des. 2013. PMID: 23116399 Review.
Structural and binding studies of a C-type galactose-binding lectin from Bothrops jararacussu snake venom.
Sartim MA, Pinheiro MP, de Pádua RAP, Sampaio SV, Nonato MC. Sartim MA, et al. Among authors: pinheiro mp. Toxicon. 2017 Feb;126:59-69. doi: 10.1016/j.toxicon.2016.12.007. Epub 2016 Dec 19. Toxicon. 2017. PMID: 28003128
The dihydroorotate dehydrogenases: Past and present.
Reis RAG, Calil FA, Feliciano PR, Pinheiro MP, Nonato MC. Reis RAG, et al. Among authors: pinheiro mp. Arch Biochem Biophys. 2017 Oct 15;632:175-191. doi: 10.1016/j.abb.2017.06.019. Epub 2017 Jun 27. Arch Biochem Biophys. 2017. PMID: 28666740 Review.
N-terminal phosphorylation of glutaminase C decreases its enzymatic activity and cancer cell migration.
Ascenção CFR, Nagampalli RSK, Islam Z, Pinheiro MP, Menezes Dos Reis L, Pauletti BA, de Guzzi Cassago CA, Granato DC, Paes Leme AF, Dias SMG. Ascenção CFR, et al. Among authors: pinheiro mp. Biochimie. 2018 Nov;154:69-76. doi: 10.1016/j.biochi.2018.07.022. Epub 2018 Aug 6. Biochimie. 2018. PMID: 30092248
The role of local residue environmental changes in thermostable mutants of the GH11 xylanase from Bacillus subtilis.
Silva SB, Pinheiro MP, Fuzo CA, Silva SR, Ferreira TL, Lourenzoni MR, Nonato MC, Vieira DS, Ward RJ. Silva SB, et al. Among authors: pinheiro mp. Int J Biol Macromol. 2017 Apr;97:574-584. doi: 10.1016/j.ijbiomac.2017.01.054. Epub 2017 Jan 18. Int J Biol Macromol. 2017. PMID: 28109807
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