Pink JJ - Search Results

1

Identification of a class of novel tubulin inhibitors.

Yi X, Zhong B, Smith KM, Geldenhuys WJ, Feng Y, Pink JJ, Dowlati A, Xu Y, Zhou A, Su B. Yi X, et al. Among authors: pink jj. J Med Chem. 2012 Apr 12;55(7):3425-35. doi: 10.1021/jm300100d. Epub 2012 Apr 2. J Med Chem. 2012. PMID: 22435708

2

From COX-2 inhibitor nimesulide to potent anti-cancer agent: synthesis, in vitro, in vivo and pharmacokinetic evaluation.

Zhong B, Cai X, Chennamaneni S, Yi X, Liu L, Pink JJ, Dowlati A, Xu Y, Zhou A, Su B. Zhong B, et al. Among authors: pink jj. Eur J Med Chem. 2012 Jan;47(1):432-444. doi: 10.1016/j.ejmech.2011.11.012. Epub 2011 Nov 15. Eur J Med Chem. 2012. PMID: 22119125 Free PMC article.

3

Synthesis and anticancer mechanism investigation of dual Hsp27 and tubulin inhibitors.

Zhong B, Chennamaneni S, Lama R, Yi X, Geldenhuys WJ, Pink JJ, Dowlati A, Xu Y, Zhou A, Su B. Zhong B, et al. Among authors: pink jj. J Med Chem. 2013 Jul 11;56(13):5306-20. doi: 10.1021/jm4004736. Epub 2013 Jun 28. J Med Chem. 2013. PMID: 23767669 Free PMC article.

4

Pharmacogenomic approach to identify drug sensitivity in small-cell lung cancer.

Wildey G, Chen Y, Lent I, Stetson L, Pink J, Barnholtz-Sloan JS, Dowlati A. Wildey G, et al. PLoS One. 2014 Sep 8;9(9):e106784. doi: 10.1371/journal.pone.0106784. eCollection 2014. PLoS One. 2014. PMID: 25198282 Free PMC article.

5

Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase.

Huff SE, Mohammed FA, Yang M, Agrawal P, Pink J, Harris ME, Dealwis CG, Viswanathan R. Huff SE, et al. J Med Chem. 2018 Feb 8;61(3):666-680. doi: 10.1021/acs.jmedchem.7b00530. Epub 2018 Jan 5. J Med Chem. 2018. PMID: 29253340 Free PMC article.

6

Quinacrine overcomes resistance to erlotinib by inhibiting FACT, NF-κB, and cell-cycle progression in non-small cell lung cancer.

Dermawan JK, Gurova K, Pink J, Dowlati A, De S, Narla G, Sharma N, Stark GR. Dermawan JK, et al. Mol Cancer Ther. 2014 Sep;13(9):2203-14. doi: 10.1158/1535-7163.MCT-14-0013. Epub 2014 Jul 15. Mol Cancer Ther. 2014. PMID: 25028470 Free PMC article.

7

Phase I clinical trial of the base excision repair inhibitor methoxyamine in combination with fludarabine for patients with advanced hematologic malignancies.

Caimi PF, Cooper BW, William BM, Dowlati A, Barr PM, Fu P, Pink J, Xu Y, Lazarus HM, de Lima M, Gerson SL. Caimi PF, et al. Oncotarget. 2017 Aug 9;8(45):79864-79875. doi: 10.18632/oncotarget.20094. eCollection 2017 Oct 3. Oncotarget. 2017. PMID: 29108368 Free PMC article.

8

Phase I trial of pelvic radiation, weekly cisplatin, and 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) for locally advanced cervical cancer.

Kunos CA, Waggoner S, von Gruenigen V, Eldermire E, Pink J, Dowlati A, Kinsella TJ. Kunos CA, et al. Clin Cancer Res. 2010 Feb 15;16(4):1298-306. doi: 10.1158/1078-0432.CCR-09-2469. Epub 2010 Feb 9. Clin Cancer Res. 2010. PMID: 20145183 Free PMC article. Clinical Trial.

9

Phase I clinical trial of temozolomide and methoxyamine (TRC-102), an inhibitor of base excision repair, in patients with advanced solid tumors.

Eads JR, Krishnamurthi SS, Saltzman J, Bokar JA, Savvides P, Meropol NJ, Gibbons J, Koon H, Sharma N, Rogers L, Pink JJ, Xu Y, Beumer JH, Riendeau J, Fu P, Gerson SL, Dowlati A. Eads JR, et al. Among authors: pink jj. Invest New Drugs. 2021 Feb;39(1):142-151. doi: 10.1007/s10637-020-00962-x. Epub 2020 Jun 17. Invest New Drugs. 2021. PMID: 32556884 Free PMC article. Clinical Trial.

10

Identification of Non-nucleoside Human Ribonucleotide Reductase Modulators.

Ahmad MF, Huff SE, Pink J, Alam I, Zhang A, Perry K, Harris ME, Misko T, Porwal SK, Oleinick NL, Miyagi M, Viswanathan R, Dealwis CG. Ahmad MF, et al. J Med Chem. 2015 Dec 24;58(24):9498-509. doi: 10.1021/acs.jmedchem.5b00929. Epub 2015 Dec 9. J Med Chem. 2015. PMID: 26488902 Free PMC article.

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