Pioszak AA - Search Results

1

Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors.

Hendrikse ER, Liew LP, Bower RL, Bonnet M, Jamaluddin MA, Prodan N, Richards KD, Walker CS, Pairaudeau G, Smith DM, Rujan RM, Sudra R, Reynolds CA, Booe JM, Pioszak AA, Flanagan JU, Hay MP, Hay DL. Hendrikse ER, et al. Among authors: pioszak aa. ACS Pharmacol Transl Sci. 2020 Mar 12;3(2):305-320. doi: 10.1021/acsptsci.9b00108. eCollection 2020 Apr 10. ACS Pharmacol Transl Sci. 2020. PMID: 32296770 Free PMC article.

2

Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs.

Lee SM, Booe JM, Pioszak AA. Lee SM, et al. Among authors: pioszak aa. Eur J Pharmacol. 2015 Sep 15;763(Pt B):196-205. doi: 10.1016/j.ejphar.2015.05.013. Epub 2015 May 14. Eur J Pharmacol. 2015. PMID: 25981303 Free PMC article. Review.

3

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.

Booe JM, Walker CS, Barwell J, Kuteyi G, Simms J, Jamaluddin MA, Warner ML, Bill RM, Harris PW, Brimble MA, Poyner DR, Hay DL, Pioszak AA. Booe JM, et al. Among authors: pioszak aa. Mol Cell. 2015 Jun 18;58(6):1040-52. doi: 10.1016/j.molcel.2015.04.018. Epub 2015 May 14. Mol Cell. 2015. PMID: 25982113 Free PMC article.

4

Receptor Activity-Modifying Proteins (RAMPs): New Insights and Roles.

Hay DL, Pioszak AA. Hay DL, et al. Among authors: pioszak aa. Annu Rev Pharmacol Toxicol. 2016;56:469-87. doi: 10.1146/annurev-pharmtox-010715-103120. Epub 2015 Oct 23. Annu Rev Pharmacol Toxicol. 2016. PMID: 26514202 Free PMC article. Review.

5

Calcitonin and Amylin Receptor Peptide Interaction Mechanisms: INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYING PROTEINS.

Lee SM, Hay DL, Pioszak AA. Lee SM, et al. Among authors: pioszak aa. J Biol Chem. 2016 Apr 15;291(16):8686-700. doi: 10.1074/jbc.M115.713628. Epub 2016 Feb 19. J Biol Chem. 2016. PMID: 26895962 Free PMC article.

6

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.

Watkins HA, Chakravarthy M, Abhayawardana RS, Gingell JJ, Garelja M, Pardamwar M, McElhinney JM, Lathbridge A, Constantine A, Harris PW, Yuen TY, Brimble MA, Barwell J, Poyner DR, Woolley MJ, Conner AC, Pioszak AA, Reynolds CA, Hay DL. Watkins HA, et al. Among authors: pioszak aa. J Biol Chem. 2016 May 27;291(22):11657-75. doi: 10.1074/jbc.M115.688218. Epub 2016 Mar 24. J Biol Chem. 2016. PMID: 27013657 Free PMC article.

7

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology.

J Gingell J, Simms J, Barwell J, Poyner DR, Watkins HA, Pioszak AA, Sexton PM, Hay DL. J Gingell J, et al. Among authors: pioszak aa. Cell Discov. 2016 May 17;2:16012. doi: 10.1038/celldisc.2016.12. eCollection 2016. Cell Discov. 2016. PMID: 27462459 Free PMC article.

8

Erratum: An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology.

Gingell JJ, Simms J, Barwell J, Poyner DR, Watkins HA, Pioszak AA, Sexton PM, Hay DL. Gingell JJ, et al. Among authors: pioszak aa. Cell Discov. 2016 Jun 21;2:16020. doi: 10.1038/celldisc.2016.20. eCollection 2016. Cell Discov. 2016. PMID: 27463403 Free PMC article.

9

Calcitonin and amylin receptor peptide interaction mechanisms. INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYING PROTEINS.

Lee SM, Hay DL, Pioszak AA. Lee SM, et al. Among authors: pioszak aa. J Biol Chem. 2016 Jul 29;291(31):16416. doi: 10.1074/jbc.A115.713628. J Biol Chem. 2016. PMID: 27474777 Free PMC article. No abstract available.

10

N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity.

Lee SM, Booe JM, Gingell JJ, Sjoelund V, Hay DL, Pioszak AA. Lee SM, et al. Among authors: pioszak aa. Biochemistry. 2017 Jul 5;56(26):3380-3393. doi: 10.1021/acs.biochem.7b00256. Epub 2017 Jun 26. Biochemistry. 2017. PMID: 28614667 Free PMC article.

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