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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Fraga MF, et al. Among authors: piris ma. Nat Genet. 2005 Apr;37(4):391-400. doi: 10.1038/ng1531. Epub 2005 Mar 13. Nat Genet. 2005. PMID: 15765097
Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma.
Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Pérez-Rosado A, Sanchez-Aguilera A, Fraga MF, Piris MA, Esteller M. Agrelo R, et al. Among authors: piris ma. J Clin Oncol. 2005 Jun 10;23(17):3940-7. doi: 10.1200/JCO.2005.11.650. Epub 2005 May 2. J Clin Oncol. 2005. PMID: 15867203
The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.
Fernandez AF, Rosales C, Lopez-Nieva P, Graña O, Ballestar E, Ropero S, Espada J, Melo SA, Lujambio A, Fraga MF, Pino I, Javierre B, Carmona FJ, Acquadro F, Steenbergen RD, Snijders PJ, Meijer CJ, Pineau P, Dejean A, Lloveras B, Capella G, Quer J, Buti M, Esteban JI, Allende H, Rodriguez-Frias F, Castellsague X, Minarovits J, Ponce J, Capello D, Gaidano G, Cigudosa JC, Gomez-Lopez G, Pisano DG, Valencia A, Piris MA, Bosch FX, Cahir-McFarland E, Kieff E, Esteller M. Fernandez AF, et al. Among authors: piris ma. Genome Res. 2009 Mar;19(3):438-51. doi: 10.1101/gr.083550.108. Epub 2009 Feb 10. Genome Res. 2009. PMID: 19208682 Free PMC article.
Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome.
Esteve-Puig R, Climent F, Piñeyro D, Domingo-Domènech E, Davalos V, Encuentra M, Rea A, Espejo-Herrera N, Soler M, Lopez M, Ortiz-Barahona V, Tapia G, Navarro JT, Cid J, Farré L, Villanueva A, Casanova I, Mangues R, Santamarina-Ojeda P, Fernández AF, Fraga MF, Piris MA, Kol N, Avrahami C, Moshitch-Moshkovitz S, Rechavi G, Sureda A, Esteller M. Esteve-Puig R, et al. Among authors: piris ma. Blood. 2021 Feb 18;137(7):994-999. doi: 10.1182/blood.2020005823. Blood. 2021. PMID: 32915956 Free PMC article. No abstract available.
Functional signatures identified in B-cell non-Hodgkin lymphoma profiles.
Aggarwal M, Sánchez-Beato M, Gómez-López G, Al-Shahrour F, Martínez N, Rodríguez A, Ruiz-Ballesteros E, Camacho FI, Pérez-Rosado A, de la Cueva P, Artiga MJ, Pisano DG, Kimby E, Dopazo J, Villuendas R, Piris MA. Aggarwal M, et al. Among authors: piris ma. Leuk Lymphoma. 2009 Oct;50(10):1699-708. doi: 10.1080/10428190903189035. Leuk Lymphoma. 2009. PMID: 19863341
NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas.
Vento-Tormo R, Rodríguez-Ubreva J, Lisio LD, Islam AB, Urquiza JM, Hernando H, López-Bigas N, Shannon-Lowe C, Martínez N, Montes-Moreno S, Piris MA, Ballestar E. Vento-Tormo R, et al. Among authors: piris ma. Nucleic Acids Res. 2014;42(17):11025-39. doi: 10.1093/nar/gku826. Epub 2014 Sep 8. Nucleic Acids Res. 2014. PMID: 25200074 Free PMC article.
Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm.
Menezes J, Acquadro F, Wiseman M, Gómez-López G, Salgado RN, Talavera-Casañas JG, Buño I, Cervera JV, Montes-Moreno S, Hernández-Rivas JM, Ayala R, Calasanz MJ, Larrayoz MJ, Brichs LF, Gonzalez-Vicent M, Pisano DG, Piris MA, Álvarez S, Cigudosa JC. Menezes J, et al. Among authors: piris ma. Leukemia. 2014 Apr;28(4):823-9. doi: 10.1038/leu.2013.283. Epub 2013 Sep 27. Leukemia. 2014. PMID: 24072100
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Puente XS, Pinyol M, Quesada V, Conde L, Ordóñez GR, Villamor N, Escaramis G, Jares P, Beà S, González-Díaz M, Bassaganyas L, Baumann T, Juan M, López-Guerra M, Colomer D, Tubío JM, López C, Navarro A, Tornador C, Aymerich M, Rozman M, Hernández JM, Puente DA, Freije JM, Velasco G, Gutiérrez-Fernández A, Costa D, Carrió A, Guijarro S, Enjuanes A, Hernández L, Yagüe J, Nicolás P, Romeo-Casabona CM, Himmelbauer H, Castillo E, Dohm JC, de Sanjosé S, Piris MA, de Alava E, San Miguel J, Royo R, Gelpí JL, Torrents D, Orozco M, Pisano DG, Valencia A, Guigó R, Bayés M, Heath S, Gut M, Klatt P, Marshall J, Raine K, Stebbings LA, Futreal PA, Stratton MR, Campbell PJ, Gut I, López-Guillermo A, Estivill X, Montserrat E, López-Otín C, Campo E. Puente XS, et al. Among authors: piris ma. Nature. 2011 Jun 5;475(7354):101-5. doi: 10.1038/nature10113. Nature. 2011. PMID: 21642962 Free PMC article.
427 results