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TGF-beta is a critical mediator of acute lung injury.
Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, Sheppard D. Pittet JF, et al. J Clin Invest. 2001 Jun;107(12):1537-44. doi: 10.1172/JCI11963. J Clin Invest. 2001. PMID: 11413161 Free PMC article.
Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism.
Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Frank J, et al. Among authors: pittet jf. J Biol Chem. 2003 Nov 7;278(45):43939-50. doi: 10.1074/jbc.M304882200. Epub 2003 Aug 20. J Biol Chem. 2003. PMID: 12930837 Free article.
280 results