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Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice.
Pitulescu ME, Schmidt I, Benedito R, Adams RH. Pitulescu ME, et al. Nat Protoc. 2010 Sep;5(9):1518-34. doi: 10.1038/nprot.2010.113. Epub 2010 Aug 12. Nat Protoc. 2010. PMID: 20725067
The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.
Shah AV, Birdsey GM, Peghaire C, Pitulescu ME, Dufton NP, Yang Y, Weinberg I, Osuna Almagro L, Payne L, Mason JC, Gerhardt H, Adams RH, Randi AM. Shah AV, et al. Among authors: pitulescu me. Nat Commun. 2017 Jul 11;8:16002. doi: 10.1038/ncomms16002. Nat Commun. 2017. PMID: 28695891 Free PMC article.
Sox17 is indispensable for acquisition and maintenance of arterial identity.
Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E. Corada M, et al. Among authors: pitulescu me. Nat Commun. 2013;4:2609. doi: 10.1038/ncomms3609. Nat Commun. 2013. PMID: 24153254 Free PMC article.
Eph/ephrin molecules--a hub for signaling and endocytosis.
Pitulescu ME, Adams RH. Pitulescu ME, et al. Genes Dev. 2010 Nov 15;24(22):2480-92. doi: 10.1101/gad.1973910. Genes Dev. 2010. PMID: 21078817 Free PMC article. Review.
Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.
Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH. Langen UH, et al. Among authors: pitulescu me. Nat Cell Biol. 2017 Mar;19(3):189-201. doi: 10.1038/ncb3476. Epub 2017 Feb 20. Nat Cell Biol. 2017. PMID: 28218908 Free PMC article.
Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.
Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP. Del Monte-Nieto G, et al. Among authors: pitulescu me. Nature. 2018 May;557(7705):439-445. doi: 10.1038/s41586-018-0110-6. Epub 2018 May 9. Nature. 2018. PMID: 29743679
Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis.
Cao J, Ehling M, März S, Seebach J, Tarbashevich K, Sixta T, Pitulescu ME, Werner AC, Flach B, Montanez E, Raz E, Adams RH, Schnittler H. Cao J, et al. Among authors: pitulescu me. Nat Commun. 2017 Dec 20;8(1):2210. doi: 10.1038/s41467-017-02373-8. Nat Commun. 2017. PMID: 29263363 Free PMC article.
Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.
Pitulescu ME, Schmidt I, Giaimo BD, Antoine T, Berkenfeld F, Ferrante F, Park H, Ehling M, Biljes D, Rocha SF, Langen UH, Stehling M, Nagasawa T, Ferrara N, Borggrefe T, Adams RH. Pitulescu ME, et al. Nat Cell Biol. 2017 Aug;19(8):915-927. doi: 10.1038/ncb3555. Epub 2017 Jul 17. Nat Cell Biol. 2017. PMID: 28714968 Free article.
Arteries are formed by vein-derived endothelial tip cells.
Xu C, Hasan SS, Schmidt I, Rocha SF, Pitulescu ME, Bussmann J, Meyen D, Raz E, Adams RH, Siekmann AF. Xu C, et al. Among authors: pitulescu me. Nat Commun. 2014 Dec 15;5:5758. doi: 10.1038/ncomms6758. Nat Commun. 2014. PMID: 25502622 Free PMC article.
Regulation of signaling interactions and receptor endocytosis in growing blood vessels.
Pitulescu ME, Adams RH. Pitulescu ME, et al. Cell Adh Migr. 2014;8(4):366-77. doi: 10.4161/19336918.2014.970010. Cell Adh Migr. 2014. PMID: 25482636 Free PMC article. Review.
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