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NOX2 complex-derived ROS as immune regulators.
Sareila O, Kelkka T, Pizzolla A, Hultqvist M, Holmdahl R. Sareila O, et al. Among authors: pizzolla a. Antioxid Redox Signal. 2011 Oct 15;15(8):2197-208. doi: 10.1089/ars.2010.3635. Epub 2011 Apr 11. Antioxid Redox Signal. 2011. PMID: 20919938 Review.
Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice.
Khmaladze Ia, Kelkka T, Guerard S, Wing K, Pizzolla A, Saxena A, Lundqvist K, Holmdahl M, Nandakumar KS, Holmdahl R. Khmaladze Ia, et al. Among authors: pizzolla a. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3669-78. doi: 10.1073/pnas.1405798111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136095 Free PMC article.
Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.
Kelkka T, Pizzolla A, Laurila JP, Friman T, Gustafsson R, Källberg E, Olsson O, Leanderson T, Rubin K, Salmi M, Jalkanen S, Holmdahl R. Kelkka T, et al. Among authors: pizzolla a. PLoS One. 2013 Dec 16;8(12):e84148. doi: 10.1371/journal.pone.0084148. eCollection 2013. PLoS One. 2013. PMID: 24358335 Free PMC article.
Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells.
Holmdahl R, Sareila O, Pizzolla A, Winter S, Hagert C, Jaakkola N, Kelkka T, Olsson LM, Wing K, Bäckdahl L. Holmdahl R, et al. Among authors: pizzolla a. Antioxid Redox Signal. 2013 Apr 20;18(12):1463-74. doi: 10.1089/ars.2012.4734. Epub 2012 Aug 17. Antioxid Redox Signal. 2013. PMID: 22900704 Review.
Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections.
Pizzolla A, Hultqvist M, Nilson B, Grimm MJ, Eneljung T, Jonsson IM, Verdrengh M, Kelkka T, Gjertsson I, Segal BH, Holmdahl R. Pizzolla A, et al. J Immunol. 2012 May 15;188(10):5003-11. doi: 10.4049/jimmunol.1103430. Epub 2012 Apr 9. J Immunol. 2012. PMID: 22491245 Free PMC article.
Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies.
Gelderman KA, Hultqvist M, Olsson LM, Bauer K, Pizzolla A, Olofsson P, Holmdahl R. Gelderman KA, et al. Among authors: pizzolla a. Antioxid Redox Signal. 2007 Oct;9(10):1541-67. doi: 10.1089/ars.2007.1569. Antioxid Redox Signal. 2007. PMID: 17678439 Review.
Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species.
Gelderman KA, Hultqvist M, Pizzolla A, Zhao M, Nandakumar KS, Mattsson R, Holmdahl R. Gelderman KA, et al. Among authors: pizzolla a. J Clin Invest. 2007 Oct;117(10):3020-8. doi: 10.1172/JCI31935. J Clin Invest. 2007. PMID: 17909630 Free PMC article.
CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species.
Pizzolla A, Gelderman KA, Hultqvist M, Vestberg M, Gustafsson K, Mattsson R, Holmdahl R. Pizzolla A, et al. Eur J Immunol. 2011 Feb;41(2):403-12. doi: 10.1002/eji.201040598. Epub 2010 Dec 23. Eur J Immunol. 2011. PMID: 21268010
A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement.
Pizzolla A, Wing K, Holmdahl R. Pizzolla A, et al. Am J Pathol. 2013 Oct;183(4):1144-1155. doi: 10.1016/j.ajpath.2013.06.019. Epub 2013 Jul 30. Am J Pathol. 2013. PMID: 23911657
Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.
Pizzolla A, Nguyen TH, Sant S, Jaffar J, Loudovaris T, Mannering SI, Thomas PG, Westall GP, Kedzierska K, Wakim LM. Pizzolla A, et al. J Clin Invest. 2018 Feb 1;128(2):721-733. doi: 10.1172/JCI96957. Epub 2018 Jan 8. J Clin Invest. 2018. PMID: 29309047 Free PMC article.
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