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TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.
Kim JB, Pjanic M, Nguyen T, Miller CL, Iyer D, Liu B, Wang T, Sazonova O, Carcamo-Orive I, Matic LP, Maegdefessel L, Hedin U, Quertermous T. Kim JB, et al. Among authors: pjanic m. PLoS Genet. 2017 May 8;13(5):e1006750. doi: 10.1371/journal.pgen.1006750. eCollection 2017 May. PLoS Genet. 2017. PMID: 28481916 Free PMC article.
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.
Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T. Iyer D, et al. Among authors: pjanic m. PLoS Genet. 2018 Oct 11;14(10):e1007681. doi: 10.1371/journal.pgen.1007681. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30307970 Free PMC article.
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.
Nurnberg ST, Cheng K, Raiesdana A, Kundu R, Miller CL, Kim JB, Arora K, Carcamo-Oribe I, Xiong Y, Tellakula N, Nanda V, Murthy N, Boisvert WA, Hedin U, Perisic L, Aldi S, Maegdefessel L, Pjanic M, Owens GK, Tallquist MD, Quertermous T. Nurnberg ST, et al. Among authors: pjanic m. PLoS Genet. 2015 May 28;11(5):e1005155. doi: 10.1371/journal.pgen.1005155. eCollection 2015 May. PLoS Genet. 2015. PMID: 26020946 Free PMC article.
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci.
Sazonova O, Zhao Y, Nürnberg S, Miller C, Pjanic M, Castano VG, Kim JB, Salfati EL, Kundaje AB, Bejerano G, Assimes T, Yang X, Quertermous T. Sazonova O, et al. Among authors: pjanic m. PLoS Genet. 2015 May 28;11(5):e1005202. doi: 10.1371/journal.pgen.1005202. eCollection 2015 May. PLoS Genet. 2015. PMID: 26020271 Free PMC article.
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases.
Nurnberg ST, Guerraty MA, Wirka RC, Rao HS, Pjanic M, Norton S, Serrano F, Perisic L, Elwyn S, Pluta J, Zhao W, Testa S, Park Y, Nguyen T, Ko YA, Wang T, Hedin U, Sinha S, Barash Y, Brown CD, Quertermous T, Rader DJ. Nurnberg ST, et al. Among authors: pjanic m. PLoS Genet. 2020 Jan 9;16(1):e1008538. doi: 10.1371/journal.pgen.1008538. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31917787 Free PMC article.
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